Detailed information NTG0240281

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: CGU45_RS12130
• Genome accession: NZ_CP022526
• Coordinates: 2514602..2515939 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain Ocean-1155
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 2509602..2520939

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CGU45_RS12105 (CGU45_12105)	pgeF	2509745..2510473 (-)	729	WP_015503650.1	peptidoglycan editing factor PgeF	-
CGU45_RS12110 (CGU45_12110)	rluD	2510470..2511432 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
CGU45_RS12115 (CGU45_12115)	-	2511578..2512603 (+)	1026	WP_021264117.1	outer membrane protein assembly factor BamD	-
CGU45_RS12120 (CGU45_12120)	-	2512760..2513005 (+)	246	WP_003102591.1	PP0621 family protein	-
CGU45_RS12125 (CGU45_12125)	pilS	2512995..2514587 (+)	1593	WP_021264116.1	two-component system sensor histidine kinase PilS	Regulator
CGU45_RS12130 (CGU45_12130)	pilR	2514602..2515939 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
CGU45_RS12135 (CGU45_12135)	thiO	2515985..2517079 (-)	1095	WP_009316267.1	glycine oxidase ThiO	-
CGU45_RS12140 (CGU45_12140)	-	2517214..2517723 (+)	510	WP_015503652.1	GspH/FimT family pseudopilin	-
CGU45_RS12145 (CGU45_12145)	-	2517829..2518335 (+)	507	WP_003094696.1	GspH/FimT family pseudopilin	-
CGU45_RS12150 (CGU45_12150)	pilV	2518326..2518883 (+)	558	WP_003094697.1	type 4a pilus minor pilin PilV	Machinery gene
CGU45_RS12155 (CGU45_12155)	pilW	2518880..2519704 (+)	825	WP_023101584.1	type 4a pilus minor pilin PilW	-
CGU45_RS12160 (CGU45_12160)	pilX	2519701..2520288 (+)	588	WP_003094700.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=240281 CGU45_RS12130 WP_003094694.1 2514602..2515939(+) (pilR) [Pseudomonas aeruginosa strain Ocean-1155]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=240281 CGU45_RS12130 WP_003094694.1 2514602..2515939(+) (pilR) [Pseudomonas aeruginosa strain Ocean-1155]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGATACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGCAGCGGCAAGGAACTGGTGGCGCGCCTGATCCACGAGCAGGGCCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAGCTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAAAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTATACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCGGCGAGCCTGAGCGAAATCGACAACCTCGAGGAC
TACCTGGAAGATATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTATCGTCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384