Detailed information NTG0023963

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: STR_RS03230
• Genome accession: NC_006449
• Coordinates: 592001..593002 (+)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus CNRZ1066
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 587001..598002

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STR_RS03210 (str0626)	smpB	588107..588571 (+)	465	WP_002950240.1	SsrA-binding protein SmpB	-
STR_RS03215 (str0627)	-	588725..590131 (+)	1407	WP_011227013.1	Cof-type HAD-IIB family hydrolase	-
STR_RS03220 (str0628)	-	590133..590498 (+)	366	WP_002950243.1	S1 RNA-binding domain-containing protein	-
STR_RS03225 (str0629)	-	590601..591686 (-)	1086	WP_011225703.1	M24 family metallopeptidase	-
STR_RS03230 (str0630)	ccpA	592001..593002 (+)	1002	WP_004197422.1	catabolite control protein A	Regulator
STR_RS09805 (str0631)	-	593061..593258 (+)	198	WP_011225705.1	hypothetical protein	-
STR_RS03235 (str0632)	-	593364..594128 (+)	765	WP_011225706.1	MmcQ/YjbR family DNA-binding protein	-
STR_RS03240 (str0633)	-	594143..595258 (+)	1116	WP_011227015.1	glycerate kinase	-
STR_RS03245 (str0634)	-	595297..595752 (-)	456	WP_002950250.1	YueI family protein	-
STR_RS03250 (str0635)	eno	595961..597265 (+)	1305	WP_011225708.1	surface-displayed alpha-enolase	-
STR_RS09810	-	597417..597601 (-)	185	Protein_578	hypothetical protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=23963 STR_RS03230 WP_004197422.1 592001..593002(+) (ccpA) [Streptococcus thermophilus CNRZ1066]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=23963 STR_RS03230 WP_004197422.1 592001..593002(+) (ccpA) [Streptococcus thermophilus CNRZ1066]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCGCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCAAGTAAAAAAACAACTACTGTAGGAGTTGTCATTCCAAATATTGTAAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCATCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCTGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGACGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGCCTCTTTGCTGCAGGCAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGACGTT
ATTCTTAATCATGGTCTAACTTTACGCCAGTCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547