Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C7A99_RS04360 Genome accession   NZ_CP028192
Coordinates   883264..883896 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain CFSAN018748     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 878264..888896
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C7A99_RS04335 (C7A99_04330) yhfG 878396..878563 (+) 168 WP_000736851.1 YhfG family protein -
  C7A99_RS04340 (C7A99_04335) fic 878553..879155 (+) 603 WP_107235575.1 putative adenosine monophosphate-protein transferase Fic -
  C7A99_RS04345 (C7A99_04340) pabA 879187..879750 (+) 564 WP_033870493.1 aminodeoxychorismate synthase component 2 -
  C7A99_RS04350 (C7A99_04345) argD 879836..881056 (+) 1221 WP_107235576.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C7A99_RS04355 (C7A99_04350) yhfK 881123..883213 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  C7A99_RS04360 (C7A99_04355) crp 883264..883896 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C7A99_RS04370 (C7A99_04365) yhfA 884198..884602 (+) 405 WP_096936416.1 OsmC family protein -
  C7A99_RS04375 (C7A99_04370) prkB 884657..885526 (-) 870 WP_001274675.1 phosphoribulokinase -
  C7A99_RS04380 (C7A99_04375) yheU 885580..885798 (-) 219 WP_000907085.1 YheU family protein -
  C7A99_RS04385 (C7A99_04380) yheT 885792..886814 (-) 1023 WP_107235577.1 hydrolase -
  C7A99_RS04390 (C7A99_04385) yheS 886814..888733 (-) 1920 WP_001551739.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=239322 C7A99_RS04360 WP_000242755.1 883264..883896(-) (crp) [Escherichia coli strain CFSAN018748]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=239322 C7A99_RS04360 WP_000242755.1 883264..883896(-) (crp) [Escherichia coli strain CFSAN018748]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGCCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467