Detailed information NTG0238341

Bioinformatically predicted

Overview

• Name: uvrB
• Type: Machinery gene
• Locus tag: C5P47_RS05210
• Genome accession: NZ_CP028140
• Coordinates: 1020586..1022577 (-)
• Length: 663 a.a.
• NCBI ID: WP_020905246.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NGAS979
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1015586..1027577

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C5P47_RS05185 (C5P47_05165)	dltD	1015876..1017126 (-)	1251	WP_002984219.1	D-alanyl-lipoteichoic acid biosynthesis protein DltD	-
C5P47_RS05190 (C5P47_05170)	dltC	1017119..1017358 (-)	240	WP_002984216.1	D-alanine--poly(phosphoribitol) ligase subunit DltC	-
C5P47_RS05195 (C5P47_05175)	dltB	1017376..1018632 (-)	1257	WP_002994626.1	D-alanyl-lipoteichoic acid biosynthesis protein DltB	-
C5P47_RS05200 (C5P47_05180)	dltA	1018629..1020167 (-)	1539	WP_002984203.1	D-alanine--poly(phosphoribitol) ligase subunit DltA	-
C5P47_RS05205 (C5P47_05185)	-	1020179..1020322 (-)	144	WP_002984200.1	teichoic acid D-Ala incorporation-associated protein DltX	-
C5P47_RS05210 (C5P47_05190)	uvrB	1020586..1022577 (-)	1992	WP_020905246.1	excinuclease ABC subunit UvrB	Machinery gene
C5P47_RS05215 (C5P47_05195)	-	1022770..1024944 (+)	2175	WP_002984191.1	ABC transporter substrate-binding protein/permease	-
C5P47_RS05220 (C5P47_05200)	-	1024944..1025684 (+)	741	WP_032464412.1	amino acid ABC transporter ATP-binding protein	-
C5P47_RS09120	-	1025832..1025984 (-)	153	WP_181876666.1	hypothetical protein	-
C5P47_RS05225 (C5P47_05205)	-	1025981..1027360 (-)	1380	WP_002992849.1	PTS transporter subunit EIIC	-

Sequence

Protein

• Length: 663 a.a.
• Molecular weight: 75648.72 Da
• Isoelectric Point: 4.6420

>NTDB_id=238341 C5P47_RS05210 WP_020905246.1 1020586..1022577(-) (uvrB) [Streptococcus pyogenes strain NGAS979]
MIDKRDDKPFKLKSKYKPSGDQPQAIESLVDNIEGGEKAQILLGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYG
EFKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATASLLERNDVIVVASVSCIYGLGSPKEYA
DSAVSLRPGQEISRDTLLNQLVDIQFERNDIDFQRGCFRVRGDVVEVFPASRDEHAFRVEFFGDEIDRICEIESLTGKTI
GEVDHLVLFPATHFVTNDEHMEQSIAKIQAELAEQLQLFESEGKLLEAQRLRQRTEYDIEMLREMGYTSGVENYSRHMDG
RSPGEPPYTLLDFFPEDFLIMIDESHMTMGQIKGMYNGDQARKQMLVDYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGEYEMSQTNTIIEQIIRPTGLLDPEIDVRPSMGQMDDLLGEINQRVARDERTFITTLTKKMAEDLTDYLKEMGVKVKYM
HSDIKTLERTEIIRDLRLGVFDVLIGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNVDGHVIMYADK
MTDSMQRAIDETARRREIQIAYNKAHGIVPQTIKKDIRGLISISKTSHNDISKEEMDYESMSRGERKEAINALQKQMQEA
AELLDFELAAQMRDLILELKLMD

Nucleotide

• Length: 1992 bp

>NTDB_id=238341 C5P47_RS05210 WP_020905246.1 1020586..1022577(-) (uvrB) [Streptococcus pyogenes strain NGAS979]
ATGATTGATAAACGTGATGATAAACCATTTAAACTAAAATCAAAGTATAAACCGTCTGGTGATCAGCCACAAGCTATTGA
AAGCCTAGTTGATAATATCGAGGGCGGAGAAAAAGCTCAGATTCTCCTAGGTGCTACAGGAACGGGAAAAACATACACCA
TGAGCCAAGTAATTAGTAAAGTAAATAAACCTACCTTAGTGATAGCTCACAATAAAACCTTAGCAGGACAATTATATGGT
GAATTTAAAGAATTTTTTCCAGACAATGCTGTGGAATATTTTGTTTCCTATTATGATTACTACCAACCTGAAGCATATGT
CCCATCAAGCGACACCTATATCGAAAAAGATAGTTCAGTCAATGATGAAATCGATAAACTTCGCCATTCAGCCACCGCTT
CTTTACTTGAGCGTAACGATGTCATAGTGGTAGCTTCTGTATCTTGTATTTATGGACTAGGTTCGCCAAAAGAGTACGCA
GATTCAGCAGTCAGCCTACGTCCAGGTCAGGAGATATCACGTGACACTTTGCTAAATCAATTAGTAGATATTCAATTTGA
GCGTAATGATATTGATTTTCAACGCGGCTGTTTTCGTGTACGTGGCGATGTTGTTGAGGTCTTTCCAGCATCCAGGGATG
AACATGCTTTTCGGGTGGAATTTTTCGGGGATGAGATTGACCGTATATGTGAAATCGAAAGTTTAACTGGGAAAACTATT
GGAGAAGTTGACCATTTGGTTTTATTTCCAGCTACTCACTTTGTAACAAATGATGAGCATATGGAGCAATCAATAGCCAA
AATTCAAGCAGAGTTAGCAGAGCAGTTACAGTTATTTGAATCTGAAGGTAAACTACTAGAAGCACAGCGATTACGCCAAA
GAACGGAATATGATATTGAAATGTTACGTGAAATGGGCTATACTAGCGGAGTCGAAAACTATTCCCGTCATATGGATGGC
AGGTCACCAGGAGAACCTCCTTATACCTTGTTAGATTTCTTCCCAGAAGATTTTTTAATTATGATTGATGAAAGTCACAT
GACAATGGGACAAATCAAAGGCATGTATAATGGTGACCAAGCCAGAAAACAAATGCTAGTTGACTATGGTTTTCGATTGC
CATCAGCTCTTGATAATCGTCCCTTAAGACGCGAGGAATTTGAAAGTCATGTGCACCAAATTGTCTATGTTTCAGCAACG
CCTGGTGAATACGAAATGTCACAGACTAATACAATTATTGAGCAAATTATTCGTCCGACTGGGCTACTTGATCCTGAAAT
TGATGTAAGGCCAAGTATGGGGCAAATGGATGATTTGTTGGGAGAAATTAACCAGCGCGTAGCGCGCGATGAACGGACGT
TCATCACAACCTTAACTAAAAAAATGGCAGAAGATTTGACTGATTATCTAAAAGAGATGGGTGTCAAGGTCAAGTATATG
CACAGTGATATTAAAACCTTAGAGCGGACAGAAATTATTCGTGATTTACGACTTGGTGTTTTTGATGTCTTGATTGGAAT
CAATCTGCTCCGTGAAGGGATTGATGTGCCAGAAGTTAGTCTTGTAGCCATTTTGGATGCTGATAAAGAGGGTTTCCTCC
GTAATGAACGCGGCTTGATTCAGACCATCGGTAGAGCAGCTCGAAACGTAGATGGTCATGTCATTATGTATGCGGACAAG
ATGACAGATTCTATGCAGCGGGCTATTGACGAAACGGCTCGTCGTCGTGAGATTCAAATAGCATATAACAAAGCGCACGG
CATCGTTCCACAAACTATAAAAAAAGACATCAGAGGCCTTATTAGTATAAGTAAAACAAGCCACAATGATATATCGAAAG
AAGAGATGGATTATGAAAGTATGTCAAGAGGAGAACGAAAAGAAGCGATCAATGCTCTGCAAAAACAAATGCAAGAGGCA
GCTGAATTACTTGATTTCGAATTGGCAGCTCAAATGCGAGACTTGATTTTAGAACTTAAATTAATGGACTAG

Domains

Predicted by InterProScan.

• Ultra-violet resistance protein B (UvrB) (556-598)

• Type III restriction enzyme, res subunit (ResIII) (17-124)

• UvrB interaction domain (UvrB_inter) (164-254)

• Helicase conserved C-terminal domain (Helicase_C) (443-548)

• UvrB/uvrC motif (UVR) (627-660)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrB	Streptococcus pneumoniae R6	84.917	100	0.849
uvrB	Streptococcus pneumoniae D39	84.917	100	0.849
uvrB	Streptococcus pneumoniae TIGR4	84.766	100	0.848