Detailed information NTG0238322

Bioinformatically predicted

Overview

• Name: vicK
• Type: Regulator
• Locus tag: C5P47_RS02495
• Genome accession: NZ_CP028140
• Coordinates: 454995..456347 (+)
• Length: 450 a.a.
• NCBI ID: WP_002985643.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NGAS979
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 449995..461347

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C5P47_RS02470 (C5P47_02460)	-	450150..450719 (+)	570	WP_032464242.1	hypothetical protein	-
C5P47_RS02475 (C5P47_02465)	-	450688..451836 (+)	1149	WP_032464243.1	acetyl-CoA C-acyltransferase	-
C5P47_RS02480 (C5P47_02470)	-	451793..453040 (+)	1248	WP_032464244.1	AMP-binding protein	-
C5P47_RS02485 (C5P47_02475)	-	453096..454130 (+)	1035	WP_011284595.1	DUF3114 domain-containing protein	-
C5P47_RS02490 (C5P47_02480)	yycF	454292..455002 (+)	711	WP_110410764.1	response regulator YycF	-
C5P47_RS02495 (C5P47_02485)	vicK	454995..456347 (+)	1353	WP_002985643.1	cell wall metabolism sensor histidine kinase VicK	Regulator
C5P47_RS02500 (C5P47_02490)	vicX	456351..457160 (+)	810	WP_002985641.1	MBL fold metallo-hydrolase	Regulator
C5P47_RS02505 (C5P47_02495)	rnc	457592..458284 (+)	693	WP_002985639.1	ribonuclease III	-

Sequence

Protein

• Length: 450 a.a.
• Molecular weight: 51439.91 Da
• Isoelectric Point: 5.5556

>NTDB_id=238322 C5P47_RS02495 WP_002985643.1 454995..456347(+) (vicK) [Streptococcus pyogenes strain NGAS979]
MTRDIIGNLSTFELAILILLVFVAFYFIHLAVRDYRNARIIRMMSHKIRYLINGRYTDIIDEKADIELMELSDQLNDLSD
VFRLTHENLAQEKNRLASILAYMSDGVLATDRSGKIIMINETARKQLNLSKEEALKKNITDLLEGDTSYTYRDLVSKTPV
VTVNSRNDMGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVTQLAVEMTNFTAFITSILNRFDLVKNQHTGTGKVYEIVRDYPITS
VWIEIDNDKMTQVIENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKTDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEEDVD

Nucleotide

• Length: 1353 bp

>NTDB_id=238322 C5P47_RS02495 WP_002985643.1 454995..456347(+) (vicK) [Streptococcus pyogenes strain NGAS979]
ATGACTAGAGATATCATTGGAAACTTATCCACATTTGAATTAGCGATCCTTATCTTACTTGTTTTTGTTGCTTTTTACTT
TATCCATCTTGCGGTGCGTGATTACCGAAATGCACGTATTATTCGGATGATGAGCCATAAAATCCGATACTTGATTAATG
GTCGCTATACTGATATAATCGACGAAAAAGCAGACATTGAGTTAATGGAGCTTTCAGACCAGTTAAATGACCTGTCAGAT
GTTTTTCGCTTGACGCATGAAAATCTTGCCCAAGAAAAAAATCGCTTGGCAAGTATTTTGGCTTATATGTCAGATGGTGT
ACTTGCTACAGACCGGTCTGGTAAAATCATCATGATTAACGAAACAGCTCGCAAGCAATTAAATTTAAGTAAAGAAGAGG
CACTAAAGAAAAACATTACAGATTTGTTAGAAGGTGATACTTCATATACCTACCGTGATTTGGTATCCAAAACACCAGTG
GTAACTGTTAATAGCCGAAATGATATGGGTGAGTTTGTCTCATTACGCTTGCGCTTTGCGTTGAATAGGAGAGAGAGTGG
TTTTATTTCGGGCTTGGTTGTGGTGCTCCATGACACCACAGAACAAGAAAAAGAAGAACGTGAACGCCGTCTTTTTGTCT
CTAATGTAAGTCATGAATTAAGGACCCCTTTAACTTCGGTTAAATCCTACTTGGAGGCTCTTGATGAAGGTGCACTTAAA
GAAGATATTGCTCCAAGTTTCATAAAAGTTTCTCTTGATGAAACTAATCGGATGATGCGTATGATTTCAGATCTTTTAAA
CCTGTCTCGGATTGATAATCAAGTAACCCAATTAGCAGTAGAGATGACTAATTTTACTGCTTTTATAACTTCTATTTTAA
ACAGATTTGATTTGGTTAAAAATCAGCATACAGGTACAGGAAAAGTCTATGAAATTGTAAGAGATTACCCTATTACCTCT
GTCTGGATTGAAATTGATAATGATAAAATGACACAGGTTATCGAGAATATTTTGAACAATGCCATTAAGTATTCTCCAGA
TGGTGGAAAAATCACAGTCCGTATGAAAACAACAGATACCCAATTAATTATTTCCATTTCAGACCAAGGACTAGGTATCC
CTAAAACAGATTTGCCTCTTATTTTTGATCGGTTCTATCGTGTAGACAAGGCAAGAAGTCGTGCCCAAGGAGGGACCGGT
CTAGGCCTTGCCATTGCTAAAGAAATCATCAAGCAGCACCATGGCTTTATCTGGGCTAAGAGTGACTATGGTAAAGGATC
GACCTTTACTATTGTCTTGCCTTATGAAAAAGATGCAGCCATCTATGAAGAATGGGAGGAAGATGTAGACTAA

Domains

Predicted by InterProScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (326-436)

• PAS fold (PAS) (95-162)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicK	Streptococcus mutans UA159	72.947	92	0.671
micB	Streptococcus pneumoniae Cp1015	67.529	94.444	0.638