Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilM   Type   Machinery gene
Locus tag   LPL_RS04825 Genome accession   NC_006369
Coordinates   1072466..1073530 (+) Length   354 a.a.
NCBI ID   WP_011215094.1    Uniprot ID   Q5WXY1
Organism   Legionella pneumophila str. Lens     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1067466..1078530
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPL_RS04815 (lpl0956) - 1068506..1070890 (-) 2385 WP_011215092.1 penicillin-binding protein 1A -
  LPL_RS04820 (lpl0957) ravI 1071042..1072049 (-) 1008 WP_011215093.1 Dot/Icm T4SS effector RavI -
  LPL_RS04825 (lpl0958) pilM 1072466..1073530 (+) 1065 WP_011215094.1 type IV pilus assembly protein PilM Machinery gene
  LPL_RS04830 (lpl0959) pilN 1073534..1074082 (+) 549 WP_011215095.1 PilN domain-containing protein Machinery gene
  LPL_RS04835 (lpl0960) pilO 1074096..1074695 (+) 600 WP_011215096.1 type 4a pilus biogenesis protein PilO Machinery gene
  LPL_RS04840 (lpl0961) pilP 1074692..1075276 (+) 585 WP_011215097.1 pilus assembly protein PilP Machinery gene
  LPL_RS04845 (lpl0962) pilQ 1075280..1077376 (+) 2097 WP_011215098.1 type IV pilus secretin PilQ Machinery gene
  LPL_RS04850 (lpl0963) aroK 1077822..1078349 (+) 528 WP_010946667.1 shikimate kinase AroK -

Sequence

Protein


Download         Length: 354 a.a.        Molecular weight: 38760.78 Da        Isoelectric Point: 5.0367

>NTDB_id=23832 LPL_RS04825 WP_011215094.1 1072466..1073530(+) (pilM) [Legionella pneumophila str. Lens]
MLKLLKPKHRSILGIDISSSAVKILEISGSGEDICVEGYGREEIPASALEGNMIKDVDVVANCIKKLVERLKFTSKNVAL
AVPDSAVISKVVQINEGLTDLEMEELVVIEADKYIPYPIDEINLDFEVLGHSAKSSSLLDVLIVASRAENVNTRVEAAHR
AGLEPKVVDVESYAVERSVQQIAQELPASGQDKIVAIVDIGANYTHLFVLHGMRLIFSREEKFGGMQLVEAIAEHYHMNL
EQAIALKNQGKLPEDYESAVLEPFKDMILLQIKRTLQFFYSTSQHGFVDHILLAGGMARQPGLAALIQEQLGVTTTVANP
LSHMSFGKKVNLDVINSDAPTLMVACGLALRHVE

Nucleotide


Download         Length: 1065 bp        

>NTDB_id=23832 LPL_RS04825 WP_011215094.1 1072466..1073530(+) (pilM) [Legionella pneumophila str. Lens]
GTGCTCAAATTGCTTAAACCTAAGCATCGTTCAATTCTTGGCATTGACATCAGTTCTTCCGCAGTGAAAATTCTGGAAAT
ATCAGGTTCCGGAGAAGACATTTGTGTTGAAGGATATGGTCGTGAAGAAATACCTGCCTCTGCCCTGGAAGGAAATATGA
TCAAGGATGTCGATGTAGTAGCGAATTGTATCAAAAAATTAGTAGAAAGATTGAAGTTTACATCTAAAAATGTGGCATTG
GCTGTACCTGATTCGGCTGTTATCAGTAAAGTAGTGCAAATTAATGAAGGGTTAACTGACCTTGAAATGGAAGAGCTTGT
CGTTATTGAGGCGGATAAGTACATTCCTTATCCCATAGATGAAATAAATCTGGATTTTGAAGTGTTAGGCCATTCAGCCA
AGAGCTCATCACTGCTTGATGTTTTAATCGTGGCATCAAGGGCAGAAAACGTTAATACCCGTGTTGAAGCAGCCCATAGA
GCAGGGCTGGAACCCAAAGTTGTTGACGTTGAGTCTTATGCAGTAGAGCGTTCAGTACAACAAATTGCGCAAGAATTACC
GGCAAGTGGGCAAGACAAAATTGTTGCAATAGTAGATATTGGAGCCAATTATACCCACTTATTTGTTTTGCATGGTATGC
GACTAATCTTTTCAAGAGAAGAAAAATTTGGAGGTATGCAACTTGTTGAAGCTATTGCAGAACACTATCATATGAATTTG
GAGCAGGCGATTGCCCTAAAAAATCAGGGTAAACTACCGGAGGACTACGAATCTGCTGTATTAGAACCTTTTAAGGATAT
GATTCTTTTGCAGATCAAACGTACTTTGCAGTTTTTTTATTCAACCAGTCAACATGGATTTGTAGACCATATTTTATTGG
CGGGAGGAATGGCAAGGCAACCAGGATTGGCAGCGCTTATTCAAGAACAGTTAGGAGTGACTACTACAGTGGCAAATCCA
CTATCCCATATGTCTTTTGGTAAAAAAGTGAATTTGGATGTGATTAACAGTGATGCGCCTACACTGATGGTGGCATGTGG
GTTGGCTTTGAGGCATGTCGAGTAA

Domains

Predicted by InterproScan.

Type IV pilus assembly protein PilM; (PilM_2)

(14-352)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5WXY1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilM Legionella pneumophila strain ERS1305867

100

100

1
  comM Acinetobacter nosocomialis M2

42.373

100

0.424
  pilM Acinetobacter baumannii D1279779

42.09

100

0.421
  comM Acinetobacter baylyi ADP1

40.678

100

0.407

Multiple sequence alignment