Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   C4X49_RS16370 Genome accession   NZ_CP028138
Coordinates   3334435..3335106 (+) Length   223 a.a.
NCBI ID   WP_005246441.1    Uniprot ID   A0A3A8ESE6
Organism   Acinetobacter baumannii strain NCIMB 8209     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 3329435..3340106
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C4X49_RS16355 (C4X49_16345) - 3329495..3331435 (-) 1941 Protein_3176 copper-translocating P-type ATPase -
  C4X49_RS16360 (C4X49_16350) - 3331489..3332421 (+) 933 WP_004812228.1 IS5-like element ISAha3 family transposase -
  C4X49_RS16365 (C4X49_16355) - 3332757..3334433 (+) 1677 WP_000916208.1 phosphoethanolamine transferase -
  C4X49_RS16370 (C4X49_16360) ciaR 3334435..3335106 (+) 672 WP_005246441.1 response regulator transcription factor Regulator
  C4X49_RS16375 (C4X49_16365) - 3335112..3335594 (+) 483 Protein_3180 two-component sensor histidine kinase -
  C4X49_RS16380 (C4X49_16370) - 3335639..3336343 (+) 705 WP_004733335.1 IS6-like element IS1008 family transposase -
  C4X49_RS16390 (C4X49_16380) - 3336607..3336993 (+) 387 WP_130089825.1 diacylglycerol kinase -
  C4X49_RS16395 (C4X49_16385) - 3337033..3337743 (+) 711 WP_130089826.1 phosphatase PAP2 family protein -
  C4X49_RS16400 (C4X49_16390) - 3337771..3338058 (-) 288 Protein_3184 sensor histidine kinase -
  C4X49_RS16410 (C4X49_16400) - 3338110..3338562 (-) 453 Protein_3185 IS6-like element IS1008 family transposase -
  C4X49_RS16415 (C4X49_16405) - 3338609..3339313 (-) 705 WP_001067784.1 IS6-like element IS1006 family transposase -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 25717.65 Da        Isoelectric Point: 5.7975

>NTDB_id=238273 C4X49_RS16370 WP_005246441.1 3334435..3335106(+) (ciaR) [Acinetobacter baumannii strain NCIMB 8209]
MHKILIIEDDFMIAESTETLLKLHQFDVHWVNNGIEGLKQLQQQVYDIVLLDLGLPMMDGMLVLKNIRQKFPNLPVLIIS
ARDQLQNRVDGLNQGADDYLIKPYEFDELLARIHALIRRSGLKNTVTDINKKLSHSGLELDLEQHIACFNDEPIELSNRE
WSILTALLMHPSKIFSKNDLEDKLYDFDSDVSSNTVEVYIHHLRAKLGKDFIRTIRGLGYRLG

Nucleotide


Download         Length: 672 bp        

>NTDB_id=238273 C4X49_RS16370 WP_005246441.1 3334435..3335106(+) (ciaR) [Acinetobacter baumannii strain NCIMB 8209]
ATGCATAAAATACTGATTATTGAAGATGACTTTATGATTGCCGAGTCGACTGAAACATTGCTCAAGCTGCATCAATTTGA
TGTGCATTGGGTCAATAATGGGATTGAGGGTTTAAAACAGTTACAGCAGCAGGTCTACGATATTGTCCTGCTCGATTTAG
GCTTGCCGATGATGGATGGCATGCTGGTGCTAAAAAATATCCGGCAGAAGTTTCCGAATTTACCGGTGCTGATTATCTCT
GCCCGGGATCAGTTACAAAATCGGGTAGATGGGCTGAATCAGGGAGCAGATGATTACTTGATTAAACCCTATGAATTTGA
CGAGCTACTGGCCCGTATTCATGCCTTAATACGCCGTAGTGGTTTAAAAAATACTGTGACAGATATAAATAAGAAATTAT
CACACAGTGGGCTGGAACTGGACCTGGAACAGCACATTGCATGCTTTAATGATGAACCGATCGAGTTATCTAATCGGGAA
TGGTCTATTCTCACTGCACTCCTCATGCATCCTAGCAAAATTTTTTCTAAAAACGATTTAGAAGACAAGCTTTATGATTT
TGATAGTGATGTAAGCAGTAATACGGTAGAAGTTTATATCCATCATCTGCGGGCAAAACTAGGAAAAGACTTCATACGTA
CCATACGTGGGCTAGGGTATCGCTTAGGATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-222)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3A8ESE6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.938

100

0.395
  ciaR Streptococcus pneumoniae D39

38.938

100

0.395
  ciaR Streptococcus pneumoniae R6

38.938

100

0.395
  ciaR Streptococcus pneumoniae TIGR4

38.938

100

0.395
  ciaR Streptococcus mutans UA159

37.445

100

0.381