Detailed information NTG0023821

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: LPP_RS13355
• Genome accession: NC_006368
• Coordinates: 3017091..3018176 (+)
• Length: 361 a.a.
• NCBI ID: WP_015961700.1
• Uniprot ID: A0A3A6UMH7
• Organism: Legionella pneumophila str. Paris
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 3012091..3023176

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LPP_RS13330 (lpp2645)	-	3012484..3013233 (-)	750	WP_014842652.1	type II CAAX prenyl endopeptidase Rce1 family protein	-
LPP_RS13335 (lpp2646)	rsmB	3013230..3014513 (-)	1284	WP_015961697.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
LPP_RS13340 (lpp2647)	fmt	3014510..3015454 (-)	945	WP_015961698.1	methionyl-tRNA formyltransferase	-
LPP_RS13345 (lpp2648)	def	3015451..3015963 (-)	513	WP_010948295.1	peptide deformylase	-
LPP_RS13350 (lpp2649)	-	3016057..3017094 (+)	1038	WP_015961699.1	LysM peptidoglycan-binding domain-containing protein	-
LPP_RS13355 (lpp2650)	dprA	3017091..3018176 (+)	1086	WP_015961700.1	DNA-processing protein DprA	Machinery gene
LPP_RS13360 (lpp2651)	-	3018166..3018603 (+)	438	WP_015961701.1	DUF494 family protein	-
LPP_RS13365 (lpp2652)	topA	3018683..3020962 (+)	2280	WP_011947523.1	type I DNA topoisomerase	-
LPP_RS13370 (lpp2653)	-	3021173..3023146 (-)	1974	WP_015961702.1	acyltransferase family protein	-

Sequence

Protein

• Length: 361 a.a.
• Molecular weight: 39559.72 Da
• Isoelectric Point: 7.2591

>NTDB_id=23821 LPP_RS13355 WP_015961700.1 3017091..3018176(+) (dprA) [Legionella pneumophila str. Paris]
MNNLQPLLALNRMKRIGPRTVLKLQKRWPDLNLMFQLSSVDLEEAGLPSWLAQTIKNFDPDFIKTDLNWLSSSENHHILT
WDSPYYPALLKEIADPPFILYAKGELSALTQPSLAIVGSRNASVTGNENARAFSREISRHGVSIVSGLALGIDAHAHLGC
LEGGGKTIAVLGTGIDCIYPRRHLKLAEQITENGLLLSEFPLKSPPIAGHFPLRNRIISGLSLCILVIEAAIKSGSLITA
RMALEQNRDVLAIPGSIHNPLARGCHYLLQQGAKLVTSVADVLDELKIEHHQFTSNKPIFSLASGKENLVKFIGFETTTI
DQIIDRSGYGMEQVTSGLAELELKGAVMAVPGGYIRCEYER

Nucleotide

• Length: 1086 bp

>NTDB_id=23821 LPP_RS13355 WP_015961700.1 3017091..3018176(+) (dprA) [Legionella pneumophila str. Paris]
ATGAATAATCTGCAACCCCTCCTCGCCCTAAACAGGATGAAAAGAATTGGCCCCCGAACCGTATTAAAACTGCAAAAAAG
ATGGCCTGATTTAAACCTTATGTTCCAACTGTCCAGTGTTGATCTGGAAGAAGCGGGCTTGCCATCCTGGTTGGCACAAA
CCATAAAAAATTTTGATCCGGACTTTATAAAAACTGATTTGAACTGGCTAAGTTCATCAGAAAATCATCATATTTTAACT
TGGGACTCCCCCTATTATCCCGCATTGCTCAAAGAAATAGCCGATCCTCCCTTCATTTTATACGCTAAAGGTGAGCTGTC
CGCCTTGACACAACCCAGCCTGGCTATTGTTGGAAGTCGCAATGCTTCTGTAACAGGAAACGAGAATGCCCGAGCGTTCT
CCAGGGAAATTTCCAGGCATGGGGTAAGCATAGTGAGTGGTTTAGCCTTGGGAATTGATGCTCATGCTCATTTAGGTTGT
CTGGAAGGAGGCGGCAAAACAATAGCCGTCTTAGGTACCGGAATTGATTGTATCTATCCGCGCCGGCATTTAAAATTAGC
TGAGCAAATTACAGAGAATGGTTTATTATTAAGCGAATTTCCTTTAAAAAGTCCACCAATTGCTGGACATTTTCCACTCA
GAAATCGTATAATAAGCGGTCTATCATTATGCATTTTGGTTATCGAGGCAGCAATTAAAAGCGGTTCTTTAATTACAGCA
AGAATGGCTCTGGAACAAAACAGAGATGTATTGGCCATTCCCGGATCGATTCATAACCCGTTAGCCAGGGGCTGCCACTA
CTTATTGCAGCAGGGTGCGAAATTAGTAACTTCAGTGGCTGATGTTCTTGATGAGCTAAAAATTGAGCACCATCAGTTCA
CTTCTAATAAACCAATTTTTTCCCTTGCCAGCGGTAAGGAAAACCTAGTAAAGTTCATTGGTTTTGAAACTACAACTATC
GATCAAATCATTGATCGTAGTGGATATGGCATGGAACAAGTCACGAGTGGACTGGCTGAACTAGAATTGAAAGGGGCTGT
GATGGCAGTGCCCGGTGGCTATATAAGGTGTGAATATGAAAGATAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (74-277)

• DprA winged helix domain (DprA_WH) (300-353)

3D structure

• AlphaFold DB: A0A3A6UMH7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Legionella pneumophila strain ERS1305867	99.723	100	0.997
dprA	Vibrio cholerae strain A1552	42.895	100	0.443
dprA	Vibrio campbellii strain DS40M4	46.505	91.136	0.424
dprA	Glaesserella parasuis strain SC1401	39.418	100	0.413