Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   I3O_RS21365 Genome accession   NZ_CP028117
Coordinates   3970696..3971328 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli O111 str. RM9322     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3965696..3976328
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I3O_RS21335 (I3O_21330) yheS 3965865..3967778 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  I3O_RS21340 (I3O_21335) yheT 3967778..3968800 (+) 1023 WP_000057362.1 hydrolase -
  I3O_RS21345 (I3O_21340) yheU 3968794..3969012 (+) 219 WP_000907085.1 YheU family protein -
  I3O_RS21350 (I3O_21345) prkB 3969066..3969935 (+) 870 WP_001274680.1 phosphoribulokinase -
  I3O_RS21355 (I3O_21350) yhfA 3969990..3970394 (-) 405 WP_001148909.1 OsmC family protein -
  I3O_RS21365 (I3O_21360) crp 3970696..3971328 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  I3O_RS21370 (I3O_21365) yhfK 3971379..3973469 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  I3O_RS21375 (I3O_21370) argD 3973536..3974756 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  I3O_RS21380 (I3O_21375) pabA 3974842..3975405 (-) 564 WP_000601850.1 aminodeoxychorismate synthase component 2 -
  I3O_RS21385 (I3O_21380) fic 3975437..3976039 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  I3O_RS21390 (I3O_21385) yhfG 3976029..3976196 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=237920 I3O_RS21365 WP_000242755.1 3970696..3971328(+) (crp) [Escherichia coli O111 str. RM9322]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=237920 I3O_RS21365 WP_000242755.1 3970696..3971328(+) (crp) [Escherichia coli O111 str. RM9322]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment