Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   I3M_RS05545 Genome accession   NZ_CP028116
Coordinates   948823..950844 (+) Length   673 a.a.
NCBI ID   WP_000042533.1    Uniprot ID   Q324B3
Organism   Escherichia coli O26 str. RM8426     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 943823..955844
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I3M_RS05525 (I3M_05505) bioB 944641..945681 (+) 1041 WP_000951213.1 biotin synthase BioB -
  I3M_RS05530 (I3M_05510) bioF 945678..946832 (+) 1155 WP_000118840.1 8-amino-7-oxononanoate synthase -
  I3M_RS05535 (I3M_05515) bioC 946819..947574 (+) 756 WP_000246805.1 malonyl-ACP O-methyltransferase BioC -
  I3M_RS05540 (I3M_05520) bioD 947567..948244 (+) 678 WP_000044868.1 dethiobiotin synthase -
  I3M_RS05545 (I3M_05525) uvrB 948823..950844 (+) 2022 WP_000042533.1 excinuclease ABC subunit UvrB Machinery gene
  I3M_RS32425 - 950881..950978 (-) 98 Protein_918 hypothetical protein -
  I3M_RS05550 (I3M_05530) yvcK 951036..951944 (-) 909 WP_001295302.1 uridine diphosphate-N-acetylglucosamine-binding protein YvcK -
  I3M_RS05555 (I3M_05535) moaA 952341..953330 (+) 990 WP_001295301.1 GTP 3',8-cyclase MoaA -
  I3M_RS05560 (I3M_05540) moaB 953352..953864 (+) 513 WP_000084632.1 molybdenum cofactor biosynthesis protein B -
  I3M_RS05565 (I3M_05545) moaC 953867..954352 (+) 486 WP_000080885.1 cyclic pyranopterin monophosphate synthase MoaC -
  I3M_RS05570 (I3M_05550) moaD 954345..954590 (+) 246 WP_000598619.1 molybdopterin synthase sulfur carrier subunit -
  I3M_RS05575 (I3M_05555) moaE 954592..955044 (+) 453 WP_000852287.1 molybdopterin synthase catalytic subunit MoaE -

Sequence

Protein


Download         Length: 673 a.a.        Molecular weight: 76226.06 Da        Isoelectric Point: 4.8843

>NTDB_id=237797 I3M_RS05545 WP_000042533.1 948823..950844(+) (uvrB) [Escherichia coli O26 str. RM8426]
MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEF
FPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLH
LTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPR
FTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGE
PPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYE
LEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDI
DTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPS
MAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELE
GLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS

Nucleotide


Download         Length: 2022 bp        

>NTDB_id=237797 I3M_RS05545 WP_000042533.1 948823..950844(+) (uvrB) [Escherichia coli O26 str. RM8426]
ATGAGTAAACCGTTCAAACTGAATTCCGCTTTTAAACCTTCTGGCGATCAGCCAGAGGCGATTCGACGTCTCGAAGAGGG
GCTGGAAGATGGCCTGGCGCACCAGACGTTACTTGGCGTGACTGGCTCCGGGAAAACATTCACCATTGCCAATGTCATTG
CTGACCTTCAGCGCCCAACCATGGTACTTGCGCCCAACAAAACGCTGGCGGCCCAGCTGTATGGCGAAATGAAAGAGTTC
TTCCCGGAAAACGCGGTGGAATATTTCGTTTCCTACTACGACTACTATCAGCCGGAAGCCTATGTACCGAGTTCCGACAC
TTTCATTGAGAAAGATGCCTCGGTTAACGAACATATTGAGCAGATGCGTTTGTCCGCCACCAAAGCGATGCTGGAGCGGC
GTGATGTGGTTGTGGTGGCGTCTGTTTCCGCGATTTATGGTCTGGGCGATCCTGATTTATATCTCAAGATGATGCTCCAT
CTCACGGTCGGTATGATTATCGATCAGCGCGCGATTCTGCGCCGACTGGCGGAGCTGCAATACGCTCGTAATGATCAAGC
ATTCCAGCGTGGTACTTTCCGCGTTCGTGGCGAGGTGATAGATATCTTCCCGGCAGAATCGGATGACATTGCACTTCGCG
TGGAACTGTTTGACGAGGAAGTGGAACGATTGTCGTTATTTGACCCGCTGACCGGGCAGATTGTTTCCACTATTCCACGT
TTTACCATCTACCCGAAAACGCACTACGTCACACCGCGCGAGCGCATCGTACAGGCGATGGAGGAGATCAAAGAAGAGCT
GGCCGCCAGACGCAAAGTGCTGTTGGAAAACAACAAACTGCTGGAAGAGCAGCGGCTGACCCAGCGTACCCAGTTTGATC
TGGAGATGATGAACGAGCTGGGCTACTGTTCGGGGATTGAAAACTACTCGCGCTTCCTCTCCGGTCGTGGACCGGGTGAG
CCACCGCCGACGCTGTTTGATTACCTCCCTGCTGATGGGCTGCTGGTGGTCGATGAATCTCACGTCACCATTCCACAAAT
TGGCGGCATGTATCGCGGTGACCGGGCGCGTAAAGAGACACTGGTGGAGTACGGCTTCCGCCTGCCATCAGCGCTGGATA
ACCGTCCGCTTAAGTTTGAAGAGTTCGAAGCATTAGCGCCGCAAACCATCTATGTTTCGGCGACGCCGGGTAATTACGAG
CTGGAAAAATCCGGCGGCGATGTGGTGGATCAGGTGGTGCGTCCAACCGGATTGCTTGACCCGATTATCGAAGTGCGGCC
GGTGGCGACACAGGTTGATGATCTTCTTTCGGAGATTCGTCAGCGAGCGGCAATTAACGAACGCGTACTGGTCACCACAC
TGACCAAGCGAATGGCGGAAGATCTTACCGAATATCTCGAAGAACACGGTGAGCGCGTGCGTTATCTTCACTCAGATATC
GACACCGTCGAGCGTATGGAGATTATCCGCGACTTGCGTCTGGGTGAGTTCGACGTATTGGTAGGGATCAACTTACTGCG
TGAAGGTCTGGATATGCCGGAAGTTTCGCTGGTGGCGATCCTCGACGCTGACAAAGAAGGCTTCCTGCGTTCCGAACGTT
CGTTGATCCAGACCATTGGTCGTGCGGCACGTAACGTTAACGGTAAAGCGATTCTCTACGGCGATAAGATCACCCCATCA
ATGGCGAAAGCGATTGGCGAAACCGAACGTCGCCGCGAGAAACAGCAGAAGTACAACGAGGAACACGGCATTACGCCGCA
AGGCTTGAACAAGAAAGTGGTCGATATCCTGGCGTTGGGGCAGAACATTGCTAAAACCAAAGCGAAGGGCAGAGGAAAAT
CGCGACCGATTGTTGAGCCGGATAATGTGCCGATGGATATGTCGCCTAAAGCGTTGCAGCAGAAAATCCATGAGCTGGAA
GGGTTGATGATGCAACACGCGCAGAATCTGGAGTTCGAAGAAGCGGCGCAAATTCGTGACCAGTTGCATCAGCTGCGTGA
GCTGTTTATCGCGGCATCGTAA

Domains

Predicted by InterProScan.

UvrB interaction domain (UvrB_inter)

(159-249)

UvrB/uvrC motif (UVR)

(634-667)

Ultra-violet resistance protein B (UvrB)

(552-593)

Type III restriction enzyme, res subunit (ResIII)

(13-92)

Helicase conserved C-terminal domain (Helicase_C)

(436-544)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q324B3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

56.372

99.108

0.559
  uvrB Streptococcus pneumoniae R6

56.222

99.108

0.557
  uvrB Streptococcus pneumoniae D39

56.222

99.108

0.557