Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   CFE88_RS01910 Genome accession   NZ_CP022247
Coordinates   359003..359632 (+) Length   209 a.a.
NCBI ID   WP_002447440.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain AMT     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 354003..364632
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CFE88_RS01880 (CFE88_01885) isaB 354107..354643 (+) 537 WP_002447446.1 immunodominant staphylococcal antigen IsaB family protein -
  CFE88_RS01885 (CFE88_01890) - 354795..355781 (-) 987 WP_088922669.1 FUSC family protein -
  CFE88_RS01890 (CFE88_01895) map 355955..356710 (+) 756 WP_002447444.1 type I methionyl aminopeptidase -
  CFE88_RS01895 (CFE88_01900) - 356868..357254 (+) 387 WP_002495657.1 hypothetical protein -
  CFE88_RS01900 (CFE88_01905) liaF 357269..357970 (+) 702 WP_002447442.1 cell wall-active antibiotics response protein LiaF -
  CFE88_RS01905 (CFE88_01910) vraS 357967..359013 (+) 1047 WP_002447441.1 sensor histidine kinase Regulator
  CFE88_RS01910 (CFE88_01915) vraR 359003..359632 (+) 630 WP_002447440.1 two-component system response regulator VraR Regulator
  CFE88_RS01915 (CFE88_01920) - 359689..360867 (-) 1179 WP_002447439.1 YihY/virulence factor BrkB family protein -
  CFE88_RS01920 (CFE88_01925) - 361273..361557 (-) 285 WP_002447438.1 YtxH domain-containing protein -
  CFE88_RS01925 (CFE88_01930) - 361565..362029 (-) 465 WP_001830437.1 low molecular weight protein-tyrosine-phosphatase -
  CFE88_RS01930 (CFE88_01935) - 362171..362386 (+) 216 WP_001830421.1 DUF1128 domain-containing protein -
  CFE88_RS01935 (CFE88_01940) - 362388..363629 (+) 1242 WP_002447437.1 aminopeptidase -
  CFE88_RS01940 (CFE88_01945) - 363710..364240 (+) 531 WP_002447436.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23612.25 Da        Isoelectric Point: 4.7218

>NTDB_id=237699 CFE88_RS01910 WP_002447440.1 359003..359632(+) (vraR) [Staphylococcus epidermidis strain AMT]
MAIKILFVDDHEMVRIGISSYLSTQEDIEVVGEGASGKEAITKAHELKPDLILMDLLMDDMDGVEATTEIKKDLPQIKVV
MLTSFIEDKEVYRALDSGVDSYILKTTSASDIADAVRKTYEGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=237699 CFE88_RS01910 WP_002447440.1 359003..359632(+) (vraR) [Staphylococcus epidermidis strain AMT]
GTGGCGATTAAAATTTTATTTGTTGATGATCATGAAATGGTAAGAATCGGTATTTCAAGCTATCTTTCAACACAAGAAGA
TATAGAAGTAGTAGGTGAGGGTGCTTCTGGTAAGGAAGCTATCACTAAAGCGCATGAGCTAAAACCAGATTTAATATTAA
TGGATTTACTTATGGACGATATGGATGGTGTAGAAGCTACTACTGAAATAAAAAAAGATTTACCTCAAATTAAAGTAGTC
ATGTTAACAAGCTTTATAGAAGATAAAGAAGTTTATCGTGCACTTGATTCTGGAGTAGATAGTTATATTTTAAAGACAAC
AAGTGCAAGTGATATAGCTGACGCTGTGCGTAAAACGTATGAAGGTGAATCAGTATTTGAACCAGAAGTGTTAGTAAAAA
TGCGCAACCGTATGAAAAAACGTGCCGAGCTTTATGAAATGTTAACAGAAAGAGAAATGGAGATCTTATTACTTATAGCT
AAAGGATACTCTAACCAAGAGATTGCAAGCGCCTCTCATATCACCATCAAAACAGTAAAAACTCATGTAAGTAACATACT
GAGTAAATTAGAAGTACAAGATCGAACACAAGCAGTAATCTATGCGTTTCAGCATAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

94.737

100

0.947
  degU Bacillus subtilis subsp. subtilis str. 168

35.268

100

0.378

Multiple sequence alignment