Detailed information NTG0237698

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: CFE88_RS01905
• Genome accession: NZ_CP022247
• Coordinates: 357967..359013 (+)
• Length: 348 a.a.
• NCBI ID: WP_002447441.1
• Uniprot ID: -
• Organism: Staphylococcus epidermidis strain AMT
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 352967..364013

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CFE88_RS01880 (CFE88_01885)	isaB	354107..354643 (+)	537	WP_002447446.1	immunodominant staphylococcal antigen IsaB family protein	-
CFE88_RS01885 (CFE88_01890)	-	354795..355781 (-)	987	WP_088922669.1	FUSC family protein	-
CFE88_RS01890 (CFE88_01895)	map	355955..356710 (+)	756	WP_002447444.1	type I methionyl aminopeptidase	-
CFE88_RS01895 (CFE88_01900)	-	356868..357254 (+)	387	WP_002495657.1	hypothetical protein	-
CFE88_RS01900 (CFE88_01905)	liaF	357269..357970 (+)	702	WP_002447442.1	cell wall-active antibiotics response protein LiaF	-
CFE88_RS01905 (CFE88_01910)	vraS	357967..359013 (+)	1047	WP_002447441.1	sensor histidine kinase	Regulator
CFE88_RS01910 (CFE88_01915)	vraR	359003..359632 (+)	630	WP_002447440.1	two-component system response regulator VraR	Regulator
CFE88_RS01915 (CFE88_01920)	-	359689..360867 (-)	1179	WP_002447439.1	YihY/virulence factor BrkB family protein	-
CFE88_RS01920 (CFE88_01925)	-	361273..361557 (-)	285	WP_002447438.1	YtxH domain-containing protein	-
CFE88_RS01925 (CFE88_01930)	-	361565..362029 (-)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
CFE88_RS01930 (CFE88_01935)	-	362171..362386 (+)	216	WP_001830421.1	DUF1128 domain-containing protein	-
CFE88_RS01935 (CFE88_01940)	-	362388..363629 (+)	1242	WP_002447437.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40114.53 Da
• Isoelectric Point: 5.8512

>NTDB_id=237698 CFE88_RS01905 WP_002447441.1 357967..359013(+) (vraS) [Staphylococcus epidermidis strain AMT]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVFLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVLHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=237698 CFE88_RS01905 WP_002447441.1 357967..359013(+) (vraS) [Staphylococcus epidermidis strain AMT]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAAGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATAGTTTTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCC
CAAATAGAAAGATCAATAGAAGGACAAACAGTGGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAGAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAGCGACTTGCTAGGGAATTGCATGATTCTGTTAGC
CAACAATTATTTGCTGCGAGCATGATGCTATCAGCAATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTGTTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTCTAGGTGAAGGTATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTTTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGTATTGAAGATCATTTGTTCAGAATTACACAAGAAGCTATTTCAAATACTTTGAGACA
TTCAAATGGTACGAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GATTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTAAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACAAGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	92.442	98.851	0.914