Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   I3S_RS14375 Genome accession   NZ_CP028110
Coordinates   2744384..2745016 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli O121 str. RM8352     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2739384..2750016
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I3S_RS14350 (I3S_14340) yhfG 2739516..2739683 (+) 168 WP_000736860.1 YhfG family protein -
  I3S_RS14355 (I3S_14345) fic 2739673..2740275 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  I3S_RS14360 (I3S_14350) pabA 2740307..2740870 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  I3S_RS14365 (I3S_14355) argD 2740956..2742176 (+) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  I3S_RS14370 (I3S_14360) yhfK 2742243..2744333 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  I3S_RS14375 (I3S_14365) crp 2744384..2745016 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  I3S_RS14385 (I3S_14375) yhfA 2745318..2745722 (+) 405 WP_001148908.1 OsmC family protein -
  I3S_RS14390 (I3S_14380) prkB 2745777..2746646 (-) 870 WP_001274680.1 phosphoribulokinase -
  I3S_RS14395 (I3S_14385) yheU 2746700..2746918 (-) 219 WP_000907085.1 YheU family protein -
  I3S_RS14400 (I3S_14390) yheT 2746912..2747934 (-) 1023 WP_000057359.1 hydrolase -
  I3S_RS14405 (I3S_14395) yheS 2747934..2749847 (-) 1914 WP_000634793.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=237667 I3S_RS14375 WP_000242755.1 2744384..2745016(-) (crp) [Escherichia coli O121 str. RM8352]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=237667 I3S_RS14375 WP_000242755.1 2744384..2745016(-) (crp) [Escherichia coli O121 str. RM8352]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467