Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C7M85_RS24545 Genome accession   NZ_CP027766
Coordinates   4562965..4563597 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2013C-3342     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4557965..4568597
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C7M85_RS24520 yhfG 4558097..4558264 (+) 168 WP_000736860.1 YhfG family protein -
  C7M85_RS24525 fic 4558254..4558856 (+) 603 WP_001504774.1 putative adenosine monophosphate-protein transferase Fic -
  C7M85_RS24530 pabA 4558888..4559451 (+) 564 WP_000601850.1 aminodeoxychorismate synthase component 2 -
  C7M85_RS24535 argD 4559537..4560757 (+) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C7M85_RS24540 yhfK 4560824..4562914 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  C7M85_RS24545 crp 4562965..4563597 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C7M85_RS24555 yhfA 4563899..4564303 (+) 405 WP_001148908.1 OsmC family protein -
  C7M85_RS24560 prkB 4564358..4565227 (-) 870 WP_001274680.1 phosphoribulokinase -
  C7M85_RS24565 yheU 4565281..4565499 (-) 219 WP_000907085.1 YheU family protein -
  C7M85_RS24570 yheT 4565493..4566515 (-) 1023 WP_000057356.1 hydrolase -
  C7M85_RS24575 yheS 4566515..4568428 (-) 1914 WP_044805017.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=237122 C7M85_RS24545 WP_000242755.1 4562965..4563597(-) (crp) [Escherichia coli strain 2013C-3342]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=237122 C7M85_RS24545 WP_000242755.1 4562965..4563597(-) (crp) [Escherichia coli strain 2013C-3342]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467