Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C6998_RS20020 Genome accession   NZ_CP027587
Coordinates   3657340..3657972 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2013C-4974     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3652340..3662972
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6998_RS19990 yheS 3652511..3654423 (+) 1913 Protein_3678 ABC transporter ATP-binding protein -
  C6998_RS19995 yheT 3654423..3655444 (+) 1022 Protein_3679 hydrolase -
  C6998_RS20000 yheU 3655438..3655656 (+) 219 WP_000907085.1 YheU family protein -
  C6998_RS20005 prkB 3655710..3656579 (+) 870 WP_001274680.1 phosphoribulokinase -
  C6998_RS20010 yhfA 3656634..3657038 (-) 405 WP_016232334.1 OsmC family protein -
  C6998_RS20020 crp 3657340..3657972 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C6998_RS20025 yhfK 3658023..3660113 (+) 2091 WP_158707938.1 YccS/YhfK family putative transporter -
  C6998_RS20030 argD 3660179..3661399 (-) 1221 WP_000963806.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C6998_RS20035 pabA 3661485..3662048 (-) 564 WP_000601849.1 aminodeoxychorismate synthase component 2 -
  C6998_RS20040 fic 3662080..3662682 (-) 603 WP_001280650.1 putative adenosine monophosphate-protein transferase Fic -
  C6998_RS20045 yhfG 3662672..3662839 (-) 168 WP_000736863.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=236414 C6998_RS20020 WP_000242755.1 3657340..3657972(+) (crp) [Escherichia coli strain 2013C-4974]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=236414 C6998_RS20020 WP_000242755.1 3657340..3657972(+) (crp) [Escherichia coli strain 2013C-4974]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGGCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467