Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C7A04_RS09860 Genome accession   NZ_CP027586
Coordinates   1796158..1796790 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2012EL-2448     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1791158..1801790
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C7A04_RS09830 yheS 1791327..1793240 (+) 1914 WP_000634793.1 ABC transporter ATP-binding protein -
  C7A04_RS09835 yheT 1793240..1794262 (+) 1023 WP_000057356.1 hydrolase -
  C7A04_RS09840 yheU 1794256..1794474 (+) 219 WP_000907085.1 YheU family protein -
  C7A04_RS09845 prkB 1794528..1795397 (+) 870 WP_001274680.1 phosphoribulokinase -
  C7A04_RS09850 yhfA 1795452..1795856 (-) 405 WP_001148908.1 OsmC family protein -
  C7A04_RS09860 crp 1796158..1796790 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C7A04_RS09865 yhfK 1796841..1798931 (+) 2091 WP_001343408.1 YccS/YhfK family putative transporter -
  C7A04_RS09870 argD 1798998..1800218 (-) 1221 WP_000963797.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C7A04_RS09875 pabA 1800304..1800867 (-) 564 WP_033557547.1 aminodeoxychorismate synthase component 2 -
  C7A04_RS09880 fic 1800899..1801501 (-) 603 WP_001280622.1 putative adenosine monophosphate-protein transferase Fic -
  C7A04_RS09885 yhfG 1801491..1801658 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=236319 C7A04_RS09860 WP_000242755.1 1796158..1796790(+) (crp) [Escherichia coli strain 2012EL-2448]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=236319 C7A04_RS09860 WP_000242755.1 1796158..1796790(+) (crp) [Escherichia coli strain 2012EL-2448]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467