Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C7A02_RS18335 Genome accession   NZ_CP027584
Coordinates   3457744..3458376 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 00-3076     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3452744..3463376
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C7A02_RS18305 yheS 3452913..3454826 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  C7A02_RS18310 yheT 3454826..3455848 (+) 1023 WP_000057405.1 hydrolase -
  C7A02_RS18315 yheU 3455842..3456060 (+) 219 WP_000907085.1 YheU family protein -
  C7A02_RS18320 prkB 3456114..3456983 (+) 870 WP_001274680.1 phosphoribulokinase -
  C7A02_RS18325 yhfA 3457038..3457442 (-) 405 WP_001148908.1 OsmC family protein -
  C7A02_RS18335 crp 3457744..3458376 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C7A02_RS18340 yhfK 3458427..3460517 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  C7A02_RS18345 argD 3460584..3461804 (-) 1221 WP_000963785.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C7A02_RS18350 pabA 3461890..3462453 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  C7A02_RS18355 fic 3462485..3463087 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  C7A02_RS18360 yhfG 3463077..3463244 (-) 168 WP_106901633.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=236260 C7A02_RS18335 WP_000242755.1 3457744..3458376(+) (crp) [Escherichia coli strain 00-3076]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=236260 C7A02_RS18335 WP_000242755.1 3457744..3458376(+) (crp) [Escherichia coli strain 00-3076]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467