Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C6999_RS26080 Genome accession   NZ_CP027582
Coordinates   4831116..4831748 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2013C-4538     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4826116..4836748
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6999_RS26055 yhfG 4826248..4826415 (+) 168 WP_000736860.1 YhfG family protein -
  C6999_RS26060 fic 4826405..4827007 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  C6999_RS26065 pabA 4827039..4827602 (+) 564 WP_000601850.1 aminodeoxychorismate synthase component 2 -
  C6999_RS26070 argD 4827688..4828908 (+) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C6999_RS26075 yhfK 4828975..4831065 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  C6999_RS26080 crp 4831116..4831748 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C6999_RS26090 yhfA 4832050..4832454 (+) 405 WP_001148908.1 OsmC family protein -
  C6999_RS26095 prkB 4832509..4833378 (-) 870 WP_001274680.1 phosphoribulokinase -
  C6999_RS26100 yheU 4833432..4833650 (-) 219 WP_000907085.1 YheU family protein -
  C6999_RS26105 yheT 4833644..4834666 (-) 1023 WP_000057356.1 hydrolase -
  C6999_RS26110 yheS 4834666..4836579 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=236195 C6999_RS26080 WP_000242755.1 4831116..4831748(-) (crp) [Escherichia coli strain 2013C-4538]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=236195 C6999_RS26080 WP_000242755.1 4831116..4831748(-) (crp) [Escherichia coli strain 2013C-4538]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467