Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C6996_RS20140 Genome accession   NZ_CP027579
Coordinates   4026749..4027381 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2013C-4282     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4021749..4032381
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6996_RS20115 yhfG 4021870..4022037 (+) 168 WP_000736860.1 YhfG family protein -
  C6996_RS20120 fic 4022027..4022629 (+) 603 WP_032303903.1 putative adenosine monophosphate-protein transferase Fic -
  C6996_RS20125 pabA 4022661..4023224 (+) 564 WP_000601871.1 aminodeoxychorismate synthase component 2 -
  C6996_RS20130 argD 4023310..4024530 (+) 1221 WP_000963760.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C6996_RS20135 yhfK 4024608..4026698 (-) 2091 WP_001353634.1 YccS/YhfK family putative transporter -
  C6996_RS20140 crp 4026749..4027381 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C6996_RS20150 yhfA 4027684..4028088 (+) 405 WP_001148908.1 OsmC family protein -
  C6996_RS20155 prkB 4028143..4029012 (-) 870 WP_001274672.1 phosphoribulokinase -
  C6996_RS20160 yheU 4029066..4029284 (-) 219 WP_000907089.1 YheU family protein -
  C6996_RS20165 yheT 4029278..4030299 (-) 1022 Protein_3731 hydrolase -
  C6996_RS20170 yheS 4030299..4032212 (-) 1914 WP_000634783.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=236107 C6996_RS20140 WP_000242755.1 4026749..4027381(-) (crp) [Escherichia coli strain 2013C-4282]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=236107 C6996_RS20140 WP_000242755.1 4026749..4027381(-) (crp) [Escherichia coli strain 2013C-4282]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment