Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   C6996_RS09325 Genome accession   NZ_CP027579
Coordinates   1818446..1820467 (-) Length   673 a.a.
NCBI ID   WP_000042541.1    Uniprot ID   B7LJY3
Organism   Escherichia coli strain 2013C-4282     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1813446..1825467
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6996_RS09315 - 1813854..1816151 (-) 2298 WP_074497602.1 pentapeptide repeat-containing protein -
  C6996_RS09320 - 1816635..1818287 (+) 1653 WP_000553521.1 hypothetical protein -
  C6996_RS09325 uvrB 1818446..1820467 (-) 2022 WP_000042541.1 excinuclease ABC subunit UvrB Machinery gene
  C6996_RS09330 bioD 1821046..1821723 (-) 678 WP_000044826.1 dethiobiotin synthase -
  C6996_RS09335 bioC 1821716..1822471 (-) 756 WP_000246779.1 malonyl-ACP O-methyltransferase BioC -
  C6996_RS09340 bioF 1822458..1823612 (-) 1155 WP_000118849.1 8-amino-7-oxononanoate synthase -
  C6996_RS09345 bioB 1823609..1824649 (-) 1041 WP_000951213.1 biotin synthase BioB -

Sequence

Protein


Download         Length: 673 a.a.        Molecular weight: 76256.08 Da        Isoelectric Point: 4.8843

>NTDB_id=236069 C6996_RS09325 WP_000042541.1 1818446..1820467(-) (uvrB) [Escherichia coli strain 2013C-4282]
MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEF
FPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLH
LTVGMIIDQRAILRRLAELQYTRNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPR
FTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGE
PPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYE
LEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDI
DTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPS
MAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELE
GLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS

Nucleotide


Download         Length: 2022 bp        

>NTDB_id=236069 C6996_RS09325 WP_000042541.1 1818446..1820467(-) (uvrB) [Escherichia coli strain 2013C-4282]
ATGAGTAAACCGTTCAAACTGAATTCCGCTTTTAAACCTTCTGGCGATCAGCCAGAGGCGATTCGACGTCTCGAAGAGGG
GCTGGAAGATGGCCTGGCGCACCAGACGTTGCTTGGCGTGACTGGCTCCGGGAAAACCTTCACCATTGCCAATGTCATTG
CTGACCTTCAGCGCCCAACCATGGTACTGGCGCCCAACAAAACGCTGGCGGCCCAGCTGTACGGCGAAATGAAAGAGTTC
TTCCCGGAAAACGCGGTGGAATATTTCGTCTCCTACTACGACTATTATCAGCCGGAAGCCTATGTACCGAGTTCCGACAC
CTTCATTGAGAAAGATGCCTCGGTAAACGAACATATCGAGCAGATGCGTTTGTCCGCCACCAAAGCGATGCTGGAGCGGC
GTGATGTGGTTGTGGTGGCATCGGTTTCCGCGATTTATGGTCTGGGCGATCCTGATTTATATCTCAAGATGATGCTCCAT
CTTACGGTCGGTATGATTATCGATCAGCGCGCGATCCTGCGTCGACTGGCGGAGCTGCAATACACCCGGAATGATCAAGC
CTTCCAGCGTGGCACTTTCCGCGTTCGTGGCGAGGTGATTGATATCTTCCCGGCAGAATCGGATGACATTGCACTTCGCG
TGGAGCTGTTTGATGAGGAAGTTGAACGATTGTCGTTATTTGACCCGCTAACCGGGCAGATTGTCTCTACTATTCCACGT
TTTACCATCTACCCGAAAACGCACTACGTCACGCCGCGCGAGCGCATCGTACAGGCGATGGAAGAGATCAAAGAAGAACT
GGCCGCCAGACGCAAAGTGCTGTTGGAGAATAACAAACTGCTGGAAGAGCAGCGGCTGACCCAGCGTACCCAGTTTGATC
TGGAGATGATGAACGAACTGGGATATTGCTCGGGCATTGAAAACTACTCACGCTTCCTCTCCGGCCGTGGACCAGGTGAG
CCACCGCCGACGCTGTTTGATTACCTGCCTGCCGATGGGCTACTGGTCGTCGATGAATCTCACGTCACCATTCCACAAAT
TGGCGGTATGTATCGTGGTGACCGGGCGCGTAAAGAGACGCTGGTGGAGTACGGTTTCCGCCTACCATCAGCGCTGGATA
ACCGTCCGCTGAAGTTTGAAGAGTTCGAAGCATTAGCGCCACAAACCATCTATGTTTCGGCGACGCCGGGTAATTACGAG
CTGGAAAAATCCGGTGGTGATGTGGTGGATCAGGTCGTACGTCCAACCGGATTGCTTGACCCGATTATCGAAGTGCGACC
GGTGGCAACACAGGTTGATGATCTTCTTTCGGAGATTCGCCAGCGAGCGGCAATTAACGAGCGTGTACTGGTCACAACAT
TGACTAAGCGGATGGCGGAAGATCTTACGGAATATCTCGAAGAACACGGCGAGCGTGTGCGTTATCTTCACTCAGATATC
GATACCGTCGAGCGCATGGAAATCATCCGCGACTTGCGTCTGGGTGAGTTCGACGTGCTGGTAGGGATCAACTTACTGCG
CGAAGGTCTGGATATGCCGGAAGTTTCGCTGGTGGCGATCCTCGACGCCGACAAAGAAGGCTTCCTGCGTTCCGAACGTT
CGTTGATCCAGACCATTGGTCGTGCGGCACGTAACGTTAACGGTAAAGCGATTCTCTACGGCGATAAGATCACCCCATCA
ATGGCGAAAGCGATTGGCGAAACCGAACGTCGCCGCGAGAAACAGCAGAAGTACAACGAGGAACACGGCATTACGCCGCA
AGGCTTGAACAAGAAAGTGGTCGATATCCTGGCGCTGGGGCAGAACATTGCTAAAACCAAAGCGAAGGGCAGAGGAAAAT
CGCGACCGATTGTTGAGCCGGATAATGTGCCGATGGATATGTCGCCTAAAGCGTTGCAGCAGAAAATCCATGAACTGGAA
GGGCTAATGATGCAACACGCGCAGAATCTGGAGTTCGAAGAAGCGGCGCAAATTCGTGACCAGTTGCATCAGCTGCGTGA
ATTGTTCATTGCGGCTTCGTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(634-667)

Ultra-violet resistance protein B (UvrB)

(552-593)

UvrB interaction domain (UvrB_inter)

(159-249)

Type III restriction enzyme, res subunit (ResIII)

(13-92)

Helicase conserved C-terminal domain (Helicase_C)

(436-544)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B7LJY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

56.372

99.108

0.559
  uvrB Streptococcus pneumoniae R6

56.222

99.108

0.557
  uvrB Streptococcus pneumoniae D39

56.222

99.108

0.557