Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C6997_RS00765 Genome accession   NZ_CP027577
Coordinates   120275..120907 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2013C-4225     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 115275..125907
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6997_RS00735 yheS 115444..117357 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  C6997_RS00740 yheT 117357..118379 (+) 1023 WP_000057356.1 hydrolase -
  C6997_RS00745 yheU 118373..118591 (+) 219 WP_000907085.1 YheU family protein -
  C6997_RS00750 prkB 118645..119514 (+) 870 WP_001274680.1 phosphoribulokinase -
  C6997_RS00755 yhfA 119569..119973 (-) 405 WP_001148908.1 OsmC family protein -
  C6997_RS00765 crp 120275..120907 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C6997_RS00770 yhfK 120958..123048 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  C6997_RS00775 argD 123115..124335 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C6997_RS00780 pabA 124421..124984 (-) 564 WP_000601850.1 aminodeoxychorismate synthase component 2 -
  C6997_RS00785 fic 125016..125618 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  C6997_RS00790 yhfG 125608..125775 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=235970 C6997_RS00765 WP_000242755.1 120275..120907(+) (crp) [Escherichia coli strain 2013C-4225]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=235970 C6997_RS00765 WP_000242755.1 120275..120907(+) (crp) [Escherichia coli strain 2013C-4225]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467