Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   A2F94_RS19180 Genome accession   NZ_CP027573
Coordinates   3638362..3638994 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2013C-4081     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3633362..3643994
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A2F94_RS19155 yhfG 3633494..3633661 (+) 168 WP_000736860.1 YhfG family protein -
  A2F94_RS19160 fic 3633651..3634253 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  A2F94_RS19165 pabA 3634285..3634848 (+) 564 WP_000601850.1 aminodeoxychorismate synthase component 2 -
  A2F94_RS19170 argD 3634934..3636154 (+) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  A2F94_RS19175 yhfK 3636221..3638311 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  A2F94_RS19180 crp 3638362..3638994 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  A2F94_RS19190 yhfA 3639296..3639700 (+) 405 WP_001148909.1 OsmC family protein -
  A2F94_RS19195 prkB 3639755..3640624 (-) 870 WP_001274680.1 phosphoribulokinase -
  A2F94_RS19200 yheU 3640678..3640896 (-) 219 WP_000907085.1 YheU family protein -
  A2F94_RS19205 yheT 3640890..3641912 (-) 1023 WP_000057362.1 hydrolase -
  A2F94_RS19210 yheS 3641912..3643825 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=235939 A2F94_RS19180 WP_000242755.1 3638362..3638994(-) (crp) [Escherichia coli strain 2013C-4081]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=235939 A2F94_RS19180 WP_000242755.1 3638362..3638994(-) (crp) [Escherichia coli strain 2013C-4081]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467