Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C6991_RS20175 Genome accession   NZ_CP027555
Coordinates   3656718..3657350 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2013C-3513     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3651718..3662350
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6991_RS20150 yhfG 3651850..3652017 (+) 168 WP_000736860.1 YhfG family protein -
  C6991_RS20155 fic 3652007..3652609 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  C6991_RS20160 pabA 3652641..3653204 (+) 564 WP_000601850.1 aminodeoxychorismate synthase component 2 -
  C6991_RS20165 argD 3653290..3654510 (+) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C6991_RS20170 yhfK 3654577..3656667 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  C6991_RS20175 crp 3656718..3657350 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C6991_RS20185 yhfA 3657652..3658056 (+) 405 WP_001148908.1 OsmC family protein -
  C6991_RS20190 prkB 3658111..3658980 (-) 870 WP_001274680.1 phosphoribulokinase -
  C6991_RS20195 yheU 3659034..3659252 (-) 219 WP_000907085.1 YheU family protein -
  C6991_RS20200 yheT 3659246..3660268 (-) 1023 WP_000057356.1 hydrolase -
  C6991_RS20205 yheS 3660268..3662181 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=235757 C6991_RS20175 WP_000242755.1 3656718..3657350(-) (crp) [Escherichia coli strain 2013C-3513]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=235757 C6991_RS20175 WP_000242755.1 3656718..3657350(-) (crp) [Escherichia coli strain 2013C-3513]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467