Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C6950_RS15835 Genome accession   NZ_CP027550
Coordinates   2983915..2984547 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2015C-4136CT1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2978915..2989547
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6950_RS15805 yheS 2979085..2980998 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  C6950_RS15810 yheT 2980998..2982019 (+) 1022 Protein_2935 hydrolase -
  C6950_RS15815 yheU 2982013..2982231 (+) 219 WP_000907085.1 YheU family protein -
  C6950_RS15820 prkB 2982285..2983154 (+) 870 WP_001274684.1 phosphoribulokinase -
  C6950_RS15825 yhfA 2983209..2983613 (-) 405 WP_001148908.1 OsmC family protein -
  C6950_RS15835 crp 2983915..2984547 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C6950_RS15840 yhfK 2984598..2986688 (+) 2091 WP_001356893.1 YccS/YhfK family putative transporter -
  C6950_RS15845 argD 2986766..2987986 (-) 1221 WP_021560063.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C6950_RS15850 pabA 2988072..2988635 (-) 564 WP_000601853.1 aminodeoxychorismate synthase component 2 -
  C6950_RS15855 fic 2988667..2989269 (-) 603 WP_001280638.1 putative adenosine monophosphate-protein transferase Fic -
  C6950_RS15860 yhfG 2989259..2989426 (-) 168 WP_000736858.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=235584 C6950_RS15835 WP_000242755.1 2983915..2984547(+) (crp) [Escherichia coli strain 2015C-4136CT1]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=235584 C6950_RS15835 WP_000242755.1 2983915..2984547(+) (crp) [Escherichia coli strain 2015C-4136CT1]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment