Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C6992_RS25475 Genome accession   NZ_CP027548
Coordinates   4803899..4804531 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2014C-3061     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4798899..4809531
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6992_RS25450 yhfG 4799031..4799198 (+) 168 WP_000736863.1 YhfG family protein -
  C6992_RS25455 fic 4799188..4799790 (+) 603 WP_001280650.1 putative adenosine monophosphate-protein transferase Fic -
  C6992_RS25460 pabA 4799822..4800385 (+) 564 WP_032142035.1 aminodeoxychorismate synthase component 2 -
  C6992_RS25465 argD 4800471..4801691 (+) 1221 WP_000963785.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C6992_RS25470 yhfK 4801758..4803848 (-) 2091 WP_001397451.1 YccS/YhfK family putative transporter -
  C6992_RS25475 crp 4803899..4804531 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C6992_RS25485 yhfA 4804833..4805237 (+) 405 WP_001148908.1 OsmC family protein -
  C6992_RS25490 prkB 4805292..4806161 (-) 870 WP_001274680.1 phosphoribulokinase -
  C6992_RS25495 yheU 4806215..4806433 (-) 219 WP_000907085.1 YheU family protein -
  C6992_RS25500 yheT 4806427..4807448 (-) 1022 Protein_4695 hydrolase -
  C6992_RS25505 yheS 4807448..4809361 (-) 1914 WP_000634793.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=235534 C6992_RS25475 WP_000242755.1 4803899..4804531(-) (crp) [Escherichia coli strain 2014C-3061]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=235534 C6992_RS25475 WP_000242755.1 4803899..4804531(-) (crp) [Escherichia coli strain 2014C-3061]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467