Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   MJ68_RS14275 Genome accession   NZ_CP027544
Coordinates   2539933..2540565 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2013C-3264     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2534933..2545565
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MJ68_RS14245 yheS 2535102..2537015 (+) 1914 WP_000634793.1 ABC transporter ATP-binding protein -
  MJ68_RS14250 yheT 2537015..2538037 (+) 1023 WP_000057352.1 hydrolase -
  MJ68_RS14255 yheU 2538031..2538249 (+) 219 WP_000907085.1 YheU family protein -
  MJ68_RS14260 prkB 2538303..2539172 (+) 870 WP_001274680.1 phosphoribulokinase -
  MJ68_RS14265 yhfA 2539227..2539631 (-) 405 WP_001148908.1 OsmC family protein -
  MJ68_RS14275 crp 2539933..2540565 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  MJ68_RS14280 yhfK 2540616..2542706 (+) 2091 WP_001397451.1 YccS/YhfK family putative transporter -
  MJ68_RS14285 argD 2542773..2543993 (-) 1221 WP_000963785.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  MJ68_RS14290 pabA 2544079..2544642 (-) 564 WP_000601858.1 aminodeoxychorismate synthase component 2 -
  MJ68_RS14295 fic 2544674..2545276 (-) 603 WP_001280650.1 putative adenosine monophosphate-protein transferase Fic -
  MJ68_RS14300 yhfG 2545266..2545433 (-) 168 WP_000736863.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=235333 MJ68_RS14275 WP_000242755.1 2539933..2540565(+) (crp) [Escherichia coli strain 2013C-3264]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=235333 MJ68_RS14275 WP_000242755.1 2539933..2540565(+) (crp) [Escherichia coli strain 2013C-3264]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment