Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   AM460_RS06615 Genome accession   NZ_CP027534
Coordinates   1296824..1297456 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain AR_0081     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1291824..1302456
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AM460_RS06590 (AM460_06595) yhfG 1291956..1292123 (+) 168 WP_000736858.1 YhfG family protein -
  AM460_RS06595 (AM460_06600) fic 1292113..1292715 (+) 603 WP_001280613.1 putative adenosine monophosphate-protein transferase Fic -
  AM460_RS06600 (AM460_06605) pabA 1292747..1293310 (+) 564 WP_000601853.1 aminodeoxychorismate synthase component 2 -
  AM460_RS06605 (AM460_06610) argD 1293396..1294616 (+) 1221 WP_000963794.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  AM460_RS06610 (AM460_06615) yhfK 1294683..1296773 (-) 2091 WP_001296470.1 YccS/YhfK family putative transporter -
  AM460_RS06615 (AM460_06620) crp 1296824..1297456 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  AM460_RS06625 (AM460_06630) yhfA 1297758..1298162 (+) 405 WP_001148908.1 OsmC family protein -
  AM460_RS06630 (AM460_06635) prkB 1298217..1299086 (-) 870 WP_001274684.1 phosphoribulokinase -
  AM460_RS06635 (AM460_06640) yheU 1299140..1299358 (-) 219 WP_000907085.1 YheU family protein -
  AM460_RS06640 (AM460_06645) yheT 1299352..1300374 (-) 1023 WP_000057364.1 hydrolase -
  AM460_RS06645 (AM460_06650) yheS 1300374..1302287 (-) 1914 WP_000634830.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=235044 AM460_RS06615 WP_000242755.1 1296824..1297456(-) (crp) [Escherichia coli strain AR_0081]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=235044 AM460_RS06615 WP_000242755.1 1296824..1297456(-) (crp) [Escherichia coli strain AR_0081]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467