Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   AM462_RS13995 Genome accession   NZ_CP027528
Coordinates   2854116..2854787 (-) Length   223 a.a.
NCBI ID   WP_016658938.1    Uniprot ID   V2UES5
Organism   Acinetobacter baumannii strain AR_0083     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 2849116..2859787
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AM462_RS13970 (AM462_13970) - 2850555..2850923 (+) 369 WP_016658943.1 antitoxin Xre/MbcA/ParS toxin-binding domain-containing protein -
  AM462_RS13975 (AM462_13975) - 2851167..2851427 (+) 261 WP_016658942.1 helix-turn-helix domain-containing protein -
  AM462_RS13980 (AM462_13980) - 2851631..2852017 (+) 387 WP_016658941.1 diacylglycerol kinase -
  AM462_RS13985 (AM462_13985) - 2852057..2852764 (+) 708 WP_016658940.1 phosphatase PAP2 family protein -
  AM462_RS13990 (AM462_13990) - 2852790..2854112 (-) 1323 WP_095705995.1 ATP-binding protein -
  AM462_RS13995 (AM462_13995) ciaR 2854116..2854787 (-) 672 WP_016658938.1 response regulator transcription factor Regulator
  AM462_RS14000 (AM462_14000) - 2854789..2856465 (-) 1677 WP_016658937.1 phosphoethanolamine transferase -
  AM462_RS14010 (AM462_14010) - 2857074..2857646 (+) 573 WP_005180682.1 LexA family protein -
  AM462_RS14015 (AM462_14015) - 2857643..2858941 (+) 1299 WP_095706047.1 Y-family DNA polymerase -
  AM462_RS14020 (AM462_14020) - 2859100..2859309 (+) 210 WP_016658935.1 hypothetical protein -
  AM462_RS14025 (AM462_14025) xseB 2859489..2859683 (-) 195 WP_005180690.1 exodeoxyribonuclease VII small subunit -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 25727.73 Da        Isoelectric Point: 5.8400

>NTDB_id=234900 AM462_RS13995 WP_016658938.1 2854116..2854787(-) (ciaR) [Acinetobacter baumannii strain AR_0083]
MHKILIIEDDFMIAESTETLLKLHQFEVYWVNNGIEGLKQLQQQVYDIVLLDLGLPMMDGMLVLKNIRQKFPNLPVLIIS
ARDQLQNRVDGLNQGADDYLIKPYEFDELLARIHALLRRSSLKNTGIDINKKLSHSGLELDLEQHIVCFNGEPIELSNRE
WSILTALLMHPSKIFSKNDLEDKLYDFDSDVSSNTVEVYIHHLRAKLGKDFIRTIRGLGYRLG

Nucleotide


Download         Length: 672 bp        

>NTDB_id=234900 AM462_RS13995 WP_016658938.1 2854116..2854787(-) (ciaR) [Acinetobacter baumannii strain AR_0083]
ATGCATAAAATACTGATTATTGAAGATGACTTTATGATTGCCGAGTCGACTGAAACATTGCTTAAACTGCATCAGTTTGA
GGTGTACTGGGTCAATAATGGGATTGAGGGTTTAAAACAGTTACAGCAGCAGGTCTACGATATTGTCCTGCTCGATTTAG
GCTTGCCGATGATGGATGGCATGCTGGTGCTAAAAAATATCCGGCAGAAGTTTCCGAATTTACCGGTACTGATTATCTCC
GCCCGGGACCAATTACAAAACCGGGTGGATGGGCTGAATCAGGGAGCAGATGATTACTTGATTAAACCCTATGAATTTGA
CGAGCTGCTGGCCCGTATTCATGCCTTGCTGCGACGTAGTAGCTTAAAAAACACCGGGATAGACATTAATAAGAAATTAT
CACACAGTGGGCTGGAACTGGACCTGGAACAGCACATCGTATGCTTTAATGGTGAACCGATCGAGTTGTCTAATCGGGAA
TGGTCTATTCTCACTGCACTCCTCATGCATCCTAGCAAAATTTTTTCTAAAAACGATTTAGAAGACAAACTTTATGATTT
CGATAGTGATGTAAGTAGTAATACTGTGGAAGTCTATATTCACCATCTGCGCGCCAAATTAGGAAAAGACTTTATACGGA
CGATCCGTGGTCTAGGATATCGCTTAGGATAG

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-222)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB V2UES5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.053

100

0.386
  ciaR Streptococcus pneumoniae D39

38.053

100

0.386
  ciaR Streptococcus pneumoniae R6

38.053

100

0.386
  ciaR Streptococcus pneumoniae TIGR4

38.053

100

0.386
  ciaR Streptococcus mutans UA159

37.445

100

0.381

Multiple sequence alignment