Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C6W75_RS01325 Genome accession   NZ_CP027462
Coordinates   273482..274114 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli isolate 07-4299     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 268482..279114
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6W75_RS01300 yhfG 268614..268781 (+) 168 WP_000736860.1 YhfG family protein -
  C6W75_RS01305 fic 268771..269373 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  C6W75_RS01310 pabA 269405..269968 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  C6W75_RS01315 argD 270054..271274 (+) 1221 WP_000963797.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C6W75_RS01320 yhfK 271341..273431 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  C6W75_RS01325 crp 273482..274114 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C6W75_RS01335 yhfA 274416..274820 (+) 405 WP_001148908.1 OsmC family protein -
  C6W75_RS01340 prkB 274875..275744 (-) 870 WP_001274680.1 phosphoribulokinase -
  C6W75_RS01345 yheU 275798..276016 (-) 219 WP_000907085.1 YheU family protein -
  C6W75_RS01350 yheT 276010..277032 (-) 1023 WP_000057405.1 hydrolase -
  C6W75_RS01355 yheS 277032..278945 (-) 1914 WP_000634793.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=234701 C6W75_RS01325 WP_000242755.1 273482..274114(-) (crp) [Escherichia coli isolate 07-4299]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=234701 C6W75_RS01325 WP_000242755.1 273482..274114(-) (crp) [Escherichia coli isolate 07-4299]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467