Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C6W78_RS20575 Genome accession   NZ_CP027461
Coordinates   3928117..3928749 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 95-3322     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3923117..3933749
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6W78_RS20545 yheS 3923286..3925199 (+) 1914 WP_033554895.1 ABC transporter ATP-binding protein -
  C6W78_RS20550 yheT 3925199..3926221 (+) 1023 WP_042020623.1 hydrolase -
  C6W78_RS20555 yheU 3926215..3926433 (+) 219 WP_000907086.1 YheU family protein -
  C6W78_RS20560 prkB 3926487..3927356 (+) 870 WP_001274684.1 phosphoribulokinase -
  C6W78_RS20565 yhfA 3927411..3927815 (-) 405 WP_001148908.1 OsmC family protein -
  C6W78_RS20575 crp 3928117..3928749 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C6W78_RS20580 yhfK 3928800..3930890 (+) 2091 WP_001304921.1 YccS/YhfK family putative transporter -
  C6W78_RS20585 argD 3930953..3932176 (-) 1224 WP_016233602.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C6W78_RS20590 pabA 3932262..3932825 (-) 564 WP_000601853.1 aminodeoxychorismate synthase component 2 -
  C6W78_RS20595 fic 3932857..3933459 (-) 603 WP_001280638.1 putative adenosine monophosphate-protein transferase Fic -
  C6W78_RS20600 yhfG 3933449..3933616 (-) 168 WP_000736858.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=234664 C6W78_RS20575 WP_000242755.1 3928117..3928749(+) (crp) [Escherichia coli strain 95-3322]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=234664 C6W78_RS20575 WP_000242755.1 3928117..3928749(+) (crp) [Escherichia coli strain 95-3322]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment