Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C6W76_RS24355 Genome accession   NZ_CP027459
Coordinates   4545061..4545693 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 90-3040     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4540061..4550693
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6W76_RS24330 yhfG 4540194..4540361 (+) 168 WP_000736863.1 YhfG family protein -
  C6W76_RS24335 fic 4540351..4540953 (+) 603 WP_001280650.1 putative adenosine monophosphate-protein transferase Fic -
  C6W76_RS24340 pabA 4540985..4541548 (+) 564 WP_000601849.1 aminodeoxychorismate synthase component 2 -
  C6W76_RS24345 argD 4541634..4542854 (+) 1221 WP_001618902.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C6W76_RS24350 yhfK 4542920..4545010 (-) 2091 WP_047087296.1 YccS/YhfK family putative transporter -
  C6W76_RS24355 crp 4545061..4545693 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C6W76_RS24365 yhfA 4545995..4546399 (+) 405 WP_001148908.1 OsmC family protein -
  C6W76_RS24370 prkB 4546454..4547323 (-) 870 WP_001274680.1 phosphoribulokinase -
  C6W76_RS24375 yheU 4547377..4547595 (-) 219 WP_000907085.1 YheU family protein -
  C6W76_RS24380 yheT 4547589..4548611 (-) 1023 WP_000057379.1 hydrolase -
  C6W76_RS24385 yheS 4548611..4550524 (-) 1914 WP_047087294.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=234595 C6W76_RS24355 WP_000242755.1 4545061..4545693(-) (crp) [Escherichia coli strain 90-3040]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=234595 C6W76_RS24355 WP_000242755.1 4545061..4545693(-) (crp) [Escherichia coli strain 90-3040]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment