Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   C6W79_RS13200 Genome accession   NZ_CP027457
Coordinates   2645425..2646084 (-) Length   219 a.a.
NCBI ID   WP_001221488.1    Uniprot ID   -
Organism   Escherichia coli strain 88-3493     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 2640425..2651084
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6W79_RS13170 - 2640539..2641486 (+) 948 WP_001305988.1 iron-siderophore ABC transporter substrate-binding protein -
  C6W79_RS13175 - 2641483..2642370 (+) 888 WP_000614954.1 MurR/RpiR family transcriptional regulator -
  C6W79_RS13180 ygiN 2642415..2642729 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  C6W79_RS13185 mdaB 2642760..2643341 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  C6W79_RS13190 ygiZ 2643699..2644028 (+) 330 WP_001613854.1 DUF2645 family protein -
  C6W79_RS13195 qseC 2644079..2645428 (-) 1350 WP_001613852.1 quorum sensing histidine kinase QseC -
  C6W79_RS13200 ciaR 2645425..2646084 (-) 660 WP_001221488.1 quorum sensing response regulator transcription factor QseB Regulator
  C6W79_RS13205 ygiW 2646236..2646628 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  C6W79_RS13210 ygiV 2646681..2647163 (+) 483 WP_000183494.1 GyrI-like domain-containing protein -
  C6W79_RS13220 parC 2647709..2649967 (+) 2259 WP_001281881.1 DNA topoisomerase IV subunit A -
  C6W79_RS13225 plsC 2650201..2650938 (+) 738 WP_000965712.1 1-acylglycerol-3-phosphate O-acyltransferase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24692.61 Da        Isoelectric Point: 6.3527

>NTDB_id=234500 C6W79_RS13200 WP_001221488.1 2645425..2646084(-) (ciaR) [Escherichia coli strain 88-3493]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQCEPVLILTA
RDALEERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=234500 C6W79_RS13200 WP_001221488.1 2645425..2646084(-) (ciaR) [Escherichia coli strain 88-3493]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGTGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGAGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365

Multiple sequence alignment