Detailed information NTG0234468

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: S100761_RS13205
• Genome accession: NZ_CP021889
• Coordinates: 2455744..2456361 (-)
• Length: 205 a.a.
• NCBI ID: WP_046160608.1
• Uniprot ID: -
• Organism: Bacillus subtilis subsp. subtilis strain SRCM100761
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2450744..2461361

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
S100761_RS13180 (S100761_02625)	rpsT	2451046..2451312 (+)	267	WP_003229989.1	30S ribosomal protein S20	-
S100761_RS13185 (S100761_02626)	holA	2451327..2452370 (-)	1044	WP_003229987.1	DNA polymerase III subunit delta	-
S100761_RS21255	-	2452410..2452559 (-)	150	WP_003229985.1	hypothetical protein	-
S100761_RS13190 (S100761_02627)	yqzM	2452600..2452734 (+)	135	WP_003229983.1	YqzM family protein	-
S100761_RS13195 (S100761_02628)	comEC	2452774..2455104 (-)	2331	WP_087614626.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
S100761_RS13200 (S100761_02629)	comEB	2455108..2455677 (-)	570	WP_003229978.1	ComE operon protein 2	-
S100761_RS13205 (S100761_02630)	comEA	2455744..2456361 (-)	618	WP_046160608.1	competence protein ComEA	Machinery gene
S100761_RS13210 (S100761_02631)	comER	2456445..2457266 (+)	822	WP_032726195.1	late competence protein ComER	-
S100761_RS13215 (S100761_02632)	yqeM	2457332..2458075 (-)	744	WP_046160609.1	class I SAM-dependent methyltransferase	-
S100761_RS13220 (S100761_02633)	rsfS	2458072..2458428 (-)	357	WP_014480315.1	ribosome silencing factor	-
S100761_RS13225 (S100761_02634)	yqeK	2458446..2459006 (-)	561	WP_014480316.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
S100761_RS13230 (S100761_02635)	nadD	2458996..2459565 (-)	570	WP_004398676.1	nicotinate-nucleotide adenylyltransferase	-
S100761_RS13235 (S100761_02636)	yhbY	2459577..2459867 (-)	291	WP_003226133.1	ribosome assembly RNA-binding protein YhbY	-
S100761_RS13240 (S100761_02637)	aroE	2459861..2460703 (-)	843	WP_014480317.1	shikimate dehydrogenase	-

Sequence

Protein

• Length: 205 a.a.
• Molecular weight: 21738.48 Da
• Isoelectric Point: 4.7284

>NTDB_id=234468 S100761_RS13205 WP_046160608.1 2455744..2456361(-) (comEA) [Bacillus subtilis subsp. subtilis strain SRCM100761]
MNWLNQHKKAIVLAASAAVFTAIMIFLATGKNKEPVKQAVPTEAENTVVKQEANNDESSETIVIDIKGAVQHPGVYEMRT
GDRVSQAIEKAGGTSEQADEAQVNLAEILQDGTVVYIPKKGEETAVQQGGGGSVQSDGGKGALVNINTATLEELQGISGV
GPSKAEAIIAYREENGRFQTIEEITKVSGIGEKLFEKIKSSITVK

Nucleotide

• Length: 618 bp

>NTDB_id=234468 S100761_RS13205 WP_046160608.1 2455744..2456361(-) (comEA) [Bacillus subtilis subsp. subtilis strain SRCM100761]
ATGAATTGGTTGAATCAGCATAAGAAAGCAATTGTTTTAGCGGCTTCTGCGGCTGTTTTCACAGCGATTATGATCTTTCT
GGCCACAGGGAAAAATAAAGAGCCGGTGAAGCAAGCTGTACCAACAGAGGCAGAAAATACAGTGGTAAAGCAGGAAGCAA
ACAACGACGAGTCAAGCGAAACAATTGTGATAGACATCAAAGGTGCTGTTCAGCATCCTGGAGTTTATGAAATGCGAACA
GGGGACAGAGTATCTCAGGCAATTGAGAAAGCGGGCGGGACCAGTGAACAAGCAGACGAAGCGCAAGTAAATTTGGCGGA
GATTTTGCAGGACGGGACAGTGGTGTACATCCCGAAAAAGGGAGAGGAAACAGCAGTGCAGCAAGGTGGCGGAGGGTCTG
TCCAAAGCGATGGAGGGAAGGGAGCGCTGGTGAATATCAATACAGCAACCTTAGAGGAGTTACAAGGCATCTCAGGGGTG
GGGCCATCCAAAGCTGAAGCTATTATTGCATACCGGGAAGAAAACGGGCGTTTCCAAACAATTGAAGAAATCACTAAGGT
TTCAGGAATAGGTGAAAAGTTATTTGAGAAAATAAAGTCTTCCATTACAGTAAAGTGA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (63-118)

• Helix-hairpin-helix motif (HHH_3) (142-203)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Bacillus subtilis subsp. subtilis str. 168	97.561	100	0.976
comEA	Staphylococcus aureus MW2	35.909	100	0.385
comEA	Staphylococcus aureus N315	35	100	0.376