Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C6W73_RS13060 Genome accession   NZ_CP027449
Coordinates   2564857..2565489 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2014C-3097     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2559857..2570489
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6W73_RS13035 yhfG 2559989..2560156 (+) 168 WP_000736860.1 YhfG family protein -
  C6W73_RS13040 fic 2560146..2560748 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  C6W73_RS13045 pabA 2560780..2561343 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  C6W73_RS13050 argD 2561429..2562649 (+) 1221 WP_000963766.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C6W73_RS13055 yhfK 2562716..2564806 (-) 2091 WP_001356072.1 YccS/YhfK family putative transporter -
  C6W73_RS13060 crp 2564857..2565489 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C6W73_RS13070 yhfA 2565791..2566195 (+) 405 WP_001148908.1 OsmC family protein -
  C6W73_RS13075 prkB 2566250..2567119 (-) 870 WP_001274680.1 phosphoribulokinase -
  C6W73_RS13080 yheU 2567173..2567391 (-) 219 WP_000907085.1 YheU family protein -
  C6W73_RS13085 yheT 2567385..2568407 (-) 1023 WP_000057405.1 hydrolase -
  C6W73_RS13090 yheS 2568407..2570320 (-) 1914 WP_000634793.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=234260 C6W73_RS13060 WP_000242755.1 2564857..2565489(-) (crp) [Escherichia coli strain 2014C-3097]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=234260 C6W73_RS13060 WP_000242755.1 2564857..2565489(-) (crp) [Escherichia coli strain 2014C-3097]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467