Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   BB162_RS03960 Genome accession   NZ_CP021869
Coordinates   704045..705394 (+) Length   449 a.a.
NCBI ID   WP_088197843.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain SG-M6     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 699045..710394
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BB162_RS03930 (BB162_03930) - 699450..700016 (+) 567 WP_000592389.1 PepSY domain-containing protein -
  BB162_RS03935 (BB162_03935) - 700065..700715 (-) 651 WP_000100034.1 amino acid ABC transporter permease -
  BB162_RS03940 (BB162_03940) - 700727..701422 (-) 696 WP_000173638.1 amino acid ABC transporter permease -
  BB162_RS03945 (BB162_03945) - 701435..702235 (-) 801 WP_000946173.1 transporter substrate-binding domain-containing protein -
  BB162_RS03950 (BB162_03950) - 702247..703002 (-) 756 WP_000053146.1 amino acid ABC transporter ATP-binding protein -
  BB162_RS03955 (BB162_03955) vicR 703342..704052 (+) 711 WP_000722052.1 response regulator YycF Regulator
  BB162_RS03960 (BB162_03960) vicK 704045..705394 (+) 1350 WP_088197843.1 cell wall metabolism sensor histidine kinase VicK Regulator
  BB162_RS03965 (BB162_03965) vicX 705398..706207 (+) 810 WP_001289498.1 MBL fold metallo-hydrolase Regulator
  BB162_RS03970 (BB162_03970) - 706210..706578 (+) 369 WP_000719384.1 YbaN family protein -
  BB162_RS03975 (BB162_03975) rnc 706753..707439 (+) 687 WP_000661526.1 ribonuclease III -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51102.19 Da        Isoelectric Point: 4.8106

>NTDB_id=234225 BB162_RS03960 WP_088197843.1 704045..705394(+) (vicK) [Streptococcus agalactiae strain SG-M6]
MNNSAANIRSFELALLFLLVFVAVYFVYLAVRDFKMSKDIRLLNWKVRDLIAGNYSDSILIQGDADLVELGESLNDLSDV
FRMAHDNLEQEKNRLASILTYMTDGVLATDRSGKIVMINETAQQQFNLAYDEALSMNIVDMLGSGSPYSFQDLVSKTPEV
VLNRRDENGEFVTLRIRFALNRRESVFISGLVAVSHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALNE
EVAPSFIKVSLDETNRMMRMISDLLSLSRIDNEVTHLDVEMTNFTAFMTSILNRFDQIRNQKTVTGKVYEIVRDYPLKSI
WVEIDTDKMTQVIDNILNNAVKYSPDGGKITVNLRTTKTQMILSISDQGLGIPKKDLPLIFDRFYRVDKARSRQQGGTGL
GLSIAKEIVKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVTYEEWEDVED

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=234225 BB162_RS03960 WP_088197843.1 704045..705394(+) (vicK) [Streptococcus agalactiae strain SG-M6]
ATGAATAATAGTGCTGCAAATATTAGGTCGTTTGAGCTAGCCTTACTTTTTTTACTAGTTTTTGTTGCTGTCTATTTTGT
TTATCTAGCGGTTAGAGATTTTAAAATGTCTAAAGATATCCGGCTTTTGAATTGGAAAGTCAGAGATTTGATAGCAGGAA
ATTATTCAGATAGTATTCTAATTCAAGGTGATGCAGATTTGGTAGAATTAGGGGAAAGTCTAAATGATTTATCTGATGTC
TTCCGAATGGCACATGATAACTTAGAACAAGAAAAGAATCGCTTAGCGAGTATCTTAACTTATATGACTGACGGTGTGCT
GGCTACAGATCGTTCAGGAAAAATCGTTATGATTAATGAGACAGCCCAACAGCAGTTCAATCTAGCATATGATGAAGCTT
TATCAATGAATATTGTTGATATGTTAGGGTCGGGAAGTCCATATTCGTTCCAAGATTTAGTCTCTAAGACGCCAGAGGTA
GTTCTTAATAGACGTGATGAAAATGGTGAATTTGTTACCTTACGGATTCGATTTGCTTTGAACCGTCGTGAAAGTGTTTT
TATTTCCGGTTTAGTTGCAGTATCACACGATGCTACTGAGCAAGAGAAAGAAGAGCGTGAAAGAAGACTTTTTGTATCTA
ATGTTTCTCATGAACTTCGTACACCTTTGACATCTGTAAAATCTTATTTAGAAGCTTTAGATGAGGGAGCGCTCAATGAA
GAAGTTGCTCCAAGCTTCATTAAGGTATCTCTAGATGAAACAAATCGTATGATGCGTATGATATCAGATTTATTAAGTTT
ATCGCGCATTGATAATGAAGTAACGCATTTAGATGTTGAAATGACGAATTTTACAGCTTTCATGACCTCAATTTTGAATC
GATTTGATCAGATTAGAAATCAAAAAACAGTCACAGGAAAAGTTTATGAAATTGTCAGAGATTATCCTCTTAAGTCAATT
TGGGTGGAAATTGATACAGATAAGATGACTCAAGTGATTGATAACATTTTAAATAATGCAGTCAAGTATTCACCAGATGG
TGGTAAGATTACAGTTAATCTACGCACAACTAAAACGCAGATGATTTTATCAATATCAGACCAAGGCTTAGGTATTCCCA
AAAAAGATTTACCTCTCATTTTTGATCGTTTTTATCGTGTTGATAAGGCGAGAAGTCGTCAACAGGGTGGGACTGGACTT
GGTTTGTCAATTGCAAAAGAAATTGTTAAGCAGCATAAGGGATTTATTTGGGCTAAGAGTGAGTATGGTAAAGGGTCTAC
TTTTACAATCGTCTTGCCTTATGATAAAGATGCTGTAACTTATGAAGAATGGGAGGACGTTGAAGATTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

PAS fold (PAS)

(94-178)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

74.334

91.982

0.684
  micB Streptococcus pneumoniae Cp1015

67.529

94.655

0.639

Multiple sequence alignment