Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   BB159_RS05440 Genome accession   NZ_CP021868
Coordinates   1039167..1040480 (-) Length   437 a.a.
NCBI ID   WP_088181600.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain SG-M8     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1034167..1045480
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BB159_RS05420 (BB159_05420) - 1035647..1036420 (-) 774 WP_000622398.1 DUF3307 domain-containing protein -
  BB159_RS05425 (BB159_05425) - 1036410..1037096 (-) 687 WP_000280308.1 SatD family protein -
  BB159_RS05430 (BB159_05430) ffh 1037163..1038728 (-) 1566 WP_000863589.1 signal recognition particle protein -
  BB159_RS05435 (BB159_05435) - 1038746..1039078 (-) 333 WP_000402075.1 putative DNA-binding protein -
  BB159_RS05440 (BB159_05440) ciaH 1039167..1040480 (-) 1314 WP_088181600.1 sensor histidine kinase Regulator
  BB159_RS05445 (BB159_05445) ciaR 1040464..1041144 (-) 681 WP_000590620.1 response regulator transcription factor Regulator
  BB159_RS05450 (BB159_05450) - 1041306..1043855 (-) 2550 WP_000859372.1 M1 family metallopeptidase -
  BB159_RS05455 (BB159_05455) phoU 1044001..1044654 (-) 654 WP_000946330.1 phosphate signaling complex protein PhoU -
  BB159_RS05460 (BB159_05460) pstB 1044688..1045446 (-) 759 WP_000193363.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 437 a.a.        Molecular weight: 49664.09 Da        Isoelectric Point: 9.4961

>NTDB_id=234183 BB159_RS05440 WP_088181600.1 1039167..1040480(-) (ciaH) [Streptococcus agalactiae strain SG-M8]
MSKPIKISKFKKNVSDSHFIHFFTVFSGIFLVMTVIILQVMRYGVYSSVDSSLKYISTHPKNYINMVMSRTAAYLDNSNI
ASVKLKPGGQTVANTDIILFTSEEEVINYFDAFSNYQFLKPNKKNLGGISELTLTNIFGQDETYHAVTVKVNNPAYPNVT
YMTAIVNIDQLVNAKERYEKIIIFVMTTFWIISIGASIYLAKWAQKPIIENYERQKAFVENASHELRTPLAVLQNRLETL
FRKPNATILENSENIASSLDEVRNMRILTTNLLNLARRDDGIKPELAVIKPTLFDSIFENYDLIAQDNGKNFTGHNMIQD
SFKTDKTLLKQLMTILFDNAIKYTDNDGSIDFTISETDKYLFLEIADNGPGISEEDKVRIFDRFYRVDKARTRQQGGFGL
GLSLAQQIVNSLRGNITVIDNKPRGSIFKIKLPKVKG

Nucleotide


Download         Length: 1314 bp        

>NTDB_id=234183 BB159_RS05440 WP_088181600.1 1039167..1040480(-) (ciaH) [Streptococcus agalactiae strain SG-M8]
ATGTCGAAACCGATTAAGATAAGTAAATTCAAAAAAAATGTCTCAGATAGTCATTTTATCCATTTTTTCACAGTTTTTAG
TGGTATTTTTCTGGTTATGACTGTTATCATCCTCCAAGTCATGCGCTATGGTGTTTATTCTTCTGTTGATAGTAGTTTAA
AGTATATCAGTACCCATCCTAAAAATTACATCAATATGGTTATGTCACGTACTGCTGCCTACCTAGATAACTCCAATATC
GCAAGTGTCAAGTTAAAACCCGGCGGTCAGACAGTAGCTAATACTGATATTATTCTTTTTACATCAGAAGAAGAAGTCAT
TAACTATTTTGACGCATTTTCAAACTATCAGTTTTTAAAACCTAATAAAAAAAATCTAGGTGGCATTAGTGAATTAACTT
TAACCAACATCTTTGGTCAAGATGAGACATATCATGCTGTCACCGTAAAAGTTAATAACCCTGCTTATCCTAATGTGACT
TACATGACAGCTATTGTTAATATTGATCAATTAGTAAATGCTAAAGAACGCTATGAAAAAATTATTATATTTGTCATGAC
TACTTTTTGGATTATTTCAATTGGAGCAAGTATCTACTTAGCTAAATGGGCACAAAAACCGATTATAGAAAACTACGAAA
GACAGAAGGCTTTTGTCGAAAATGCTAGCCACGAGCTGCGTACTCCCCTAGCTGTCTTACAAAATCGCCTAGAAACACTA
TTCAGAAAACCGAATGCCACCATTTTAGAAAATAGTGAAAATATCGCTTCAAGTCTAGATGAAGTACGAAATATGCGTAT
TTTAACCACTAATCTTTTAAACTTAGCAAGACGTGATGATGGAATCAAACCAGAATTAGCTGTTATTAAGCCTACACTTT
TTGATAGTATCTTTGAGAATTATGATCTAATCGCCCAAGATAATGGTAAAAATTTTACTGGACATAATATGATCCAAGAT
AGTTTCAAAACAGATAAGACACTGCTAAAACAACTCATGACTATTTTATTTGATAATGCTATAAAATATACTGACAATGA
TGGTAGCATTGACTTTACCATATCTGAAACTGATAAGTATCTCTTTTTAGAAATCGCTGATAATGGACCAGGAATTTCAG
AGGAGGATAAAGTCAGAATTTTTGATCGTTTTTACCGTGTTGACAAAGCAAGAACACGACAACAAGGAGGGTTTGGCCTC
GGCCTTTCTTTAGCTCAACAAATCGTTAACTCACTGCGAGGTAATATTACAGTAATTGATAATAAACCTAGAGGCAGTAT
TTTTAAGATAAAACTACCAAAAGTAAAAGGTTAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(216-281)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

60.14

98.169

0.59
  ciaH Streptococcus pneumoniae Rx1

51.905

96.11

0.499
  ciaH Streptococcus pneumoniae D39

51.905

96.11

0.499
  ciaH Streptococcus pneumoniae R6

51.905

96.11

0.499
  ciaH Streptococcus pneumoniae TIGR4

51.905

96.11

0.499

Multiple sequence alignment