Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C6W72_RS15915 Genome accession   NZ_CP027447
Coordinates   3021536..3022168 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2014C-3075     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3016536..3027168
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6W72_RS15885 yheS 3016705..3018618 (+) 1914 WP_000634789.1 ABC transporter ATP-binding protein -
  C6W72_RS15890 yheT 3018618..3019640 (+) 1023 WP_022646191.1 hydrolase -
  C6W72_RS15895 yheU 3019634..3019852 (+) 219 WP_000907085.1 YheU family protein -
  C6W72_RS15900 prkB 3019906..3020775 (+) 870 WP_001274680.1 phosphoribulokinase -
  C6W72_RS15905 yhfA 3020830..3021234 (-) 405 WP_001148908.1 OsmC family protein -
  C6W72_RS15915 crp 3021536..3022168 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C6W72_RS15920 yhfK 3022219..3024309 (+) 2091 WP_022646192.1 YccS/YhfK family putative transporter -
  C6W72_RS15925 argD 3024376..3025596 (-) 1221 WP_096986907.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C6W72_RS15930 pabA 3025682..3026245 (-) 564 WP_096986908.1 aminodeoxychorismate synthase component 2 -
  C6W72_RS15935 fic 3026277..3026879 (-) 603 WP_096986909.1 putative adenosine monophosphate-protein transferase Fic -
  C6W72_RS15940 yhfG 3026869..3027036 (-) 168 WP_000736858.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=234178 C6W72_RS15915 WP_000242755.1 3021536..3022168(+) (crp) [Escherichia coli strain 2014C-3075]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=234178 C6W72_RS15915 WP_000242755.1 3021536..3022168(+) (crp) [Escherichia coli strain 2014C-3075]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467