Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   MJ69_RS16660 Genome accession   NZ_CP027442
Coordinates   2941987..2942619 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2013C-3252     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2936987..2947619
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MJ69_RS16630 yheS 2937157..2939070 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  MJ69_RS16635 yheT 2939070..2940091 (+) 1022 Protein_3093 hydrolase -
  MJ69_RS16640 yheU 2940085..2940303 (+) 219 WP_000907085.1 YheU family protein -
  MJ69_RS16645 prkB 2940357..2941226 (+) 870 WP_001274680.1 phosphoribulokinase -
  MJ69_RS16650 yhfA 2941281..2941685 (-) 405 WP_001148908.1 OsmC family protein -
  MJ69_RS16660 crp 2941987..2942619 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  MJ69_RS16665 yhfK 2942670..2944760 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  MJ69_RS16670 argD 2944827..2946047 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  MJ69_RS16675 pabA 2946133..2946696 (-) 564 WP_000601850.1 aminodeoxychorismate synthase component 2 -
  MJ69_RS16680 fic 2946728..2947330 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  MJ69_RS16685 yhfG 2947320..2947487 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=234015 MJ69_RS16660 WP_000242755.1 2941987..2942619(+) (crp) [Escherichia coli strain 2013C-3252]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=234015 MJ69_RS16660 WP_000242755.1 2941987..2942619(+) (crp) [Escherichia coli strain 2013C-3252]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment