Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C6W65_RS17715 Genome accession   NZ_CP027437
Coordinates   3494132..3494764 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2012C-4221     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3489132..3499764
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6W65_RS17690 yhfG 3489264..3489431 (+) 168 WP_000736860.1 YhfG family protein -
  C6W65_RS17695 fic 3489421..3490023 (+) 603 WP_001280645.1 putative adenosine monophosphate-protein transferase Fic -
  C6W65_RS17700 pabA 3490055..3490618 (+) 564 WP_106906551.1 aminodeoxychorismate synthase component 2 -
  C6W65_RS17705 argD 3490704..3491924 (+) 1221 WP_000963813.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C6W65_RS17710 yhfK 3491991..3494081 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  C6W65_RS17715 crp 3494132..3494764 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C6W65_RS17725 yhfA 3495066..3495470 (+) 405 WP_001148908.1 OsmC family protein -
  C6W65_RS17730 prkB 3495525..3496394 (-) 870 WP_106906552.1 phosphoribulokinase -
  C6W65_RS17735 yheU 3496448..3496666 (-) 219 WP_000907085.1 YheU family protein -
  C6W65_RS17740 yheT 3496660..3497682 (-) 1023 WP_106906553.1 hydrolase -
  C6W65_RS17745 yheS 3497682..3499601 (-) 1920 WP_001551739.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=233875 C6W65_RS17715 WP_000242755.1 3494132..3494764(-) (crp) [Escherichia coli strain 2012C-4221]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=233875 C6W65_RS17715 WP_000242755.1 3494132..3494764(-) (crp) [Escherichia coli strain 2012C-4221]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGATGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment