Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   ND02_RS26880 Genome accession   NZ_CP027435
Coordinates   5028888..5029520 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2014C-3599     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5023888..5034520
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ND02_RS26850 yheS 5024057..5025970 (+) 1914 WP_000634793.1 ABC transporter ATP-binding protein -
  ND02_RS26855 yheT 5025970..5026992 (+) 1023 WP_000057359.1 hydrolase -
  ND02_RS26860 yheU 5026986..5027204 (+) 219 WP_000907085.1 YheU family protein -
  ND02_RS26865 prkB 5027258..5028127 (+) 870 WP_001274680.1 phosphoribulokinase -
  ND02_RS26870 yhfA 5028182..5028586 (-) 405 WP_001148908.1 OsmC family protein -
  ND02_RS26880 crp 5028888..5029520 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  ND02_RS26885 yhfK 5029571..5031661 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  ND02_RS26890 argD 5031728..5032948 (-) 1221 WP_032212879.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  ND02_RS26895 pabA 5033034..5033597 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  ND02_RS26900 fic 5033629..5034231 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  ND02_RS26905 yhfG 5034221..5034388 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=233814 ND02_RS26880 WP_000242755.1 5028888..5029520(+) (crp) [Escherichia coli strain 2014C-3599]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=233814 ND02_RS26880 WP_000242755.1 5028888..5029520(+) (crp) [Escherichia coli strain 2014C-3599]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467