Detailed information    

insolico Bioinformatically predicted

Overview

Name   comC   Type   Machinery gene
Locus tag   CA592_RS14495 Genome accession   NZ_CP021838
Coordinates   2720468..2721217 (+) Length   249 a.a.
NCBI ID   WP_088223693.1    Uniprot ID   -
Organism   Anoxybacillus flavithermus strain 52-1A     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2715468..2726217
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CA592_RS14475 (CA592_14475) - 2715873..2717534 (+) 1662 WP_088223689.1 GspE/PulE family protein -
  CA592_RS14480 (CA592_14480) pilT 2717550..2718584 (+) 1035 WP_088223690.1 type IV pilus twitching motility protein PilT Machinery gene
  CA592_RS14485 (CA592_14485) - 2718590..2719801 (+) 1212 WP_088223691.1 type II secretion system F family protein -
  CA592_RS14490 (CA592_14490) - 2719878..2720396 (+) 519 WP_088223692.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  CA592_RS14495 (CA592_14495) comC 2720468..2721217 (+) 750 WP_088223693.1 prepilin peptidase Machinery gene
  CA592_RS14500 (CA592_14500) pilM 2721230..2722198 (+) 969 WP_088223694.1 type IV pilus biogenesis protein PilM -
  CA592_RS14505 (CA592_14505) - 2722182..2722763 (+) 582 WP_088223695.1 PilN domain-containing protein -
  CA592_RS14510 (CA592_14510) pilO 2722760..2723386 (+) 627 WP_088223696.1 type 4a pilus biogenesis protein PilO -
  CA592_RS14515 (CA592_14515) - 2723399..2723848 (+) 450 WP_088223697.1 type IV pilin protein -
  CA592_RS14520 (CA592_14520) - 2723955..2724722 (+) 768 WP_088223698.1 SPOR domain-containing protein -
  CA592_RS14525 (CA592_14525) - 2724839..2725408 (+) 570 WP_035018494.1 Maf family protein -
  CA592_RS14530 (CA592_14530) radC 2725437..2726111 (+) 675 WP_003396335.1 RadC family protein -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 27368.20 Da        Isoelectric Point: 9.4313

>NTDB_id=233722 CA592_RS14495 WP_088223693.1 2720468..2721217(+) (comC) [Anoxybacillus flavithermus strain 52-1A]
MLFFISFLLGLFLGSFYNVVGLRVPKGESIVAPRSHCPHCKRTLTAFELIPVVSYVLQKGKCRACSARISFFYPFVELST
AILFTLAPLFVGWSAEIVVSWTLISLFVIIFVSDVHYMVIPNRILLFFAPLLLIERITLAPLTPWWDSLLGSFVGFMMLF
LIALVSKGGMGGGDIKLFAVIGLALGVKLTVLAFFLSTFVGTMFGLIGMAIGHVKRGEPMPFGPAIVVGTLVAYFFGETI
IDAYVKVMM

Nucleotide


Download         Length: 750 bp        

>NTDB_id=233722 CA592_RS14495 WP_088223693.1 2720468..2721217(+) (comC) [Anoxybacillus flavithermus strain 52-1A]
ATGTTGTTTTTTATTTCTTTCCTCCTCGGTCTTTTTCTTGGCTCATTTTATAATGTTGTCGGGCTAAGGGTGCCGAAAGG
GGAGTCGATTGTTGCGCCGCGTTCGCATTGTCCGCATTGTAAGCGAACGTTAACGGCGTTTGAATTAATTCCGGTCGTGT
CGTATGTGTTACAAAAAGGGAAATGTCGCGCATGTTCGGCGCGCATTTCCTTTTTTTACCCATTCGTTGAGCTGTCCACA
GCGATATTGTTTACGCTTGCCCCACTTTTTGTCGGTTGGTCAGCAGAAATCGTCGTTAGTTGGACGCTCATTTCTTTATT
CGTTATTATTTTCGTTTCAGATGTGCATTATATGGTCATTCCAAATCGTATTTTGTTGTTTTTTGCCCCACTTCTTCTCA
TTGAGCGTATAACGCTCGCCCCATTGACACCGTGGTGGGATAGTTTGCTCGGTAGTTTTGTTGGATTTATGATGTTGTTT
CTTATTGCCCTTGTGAGTAAAGGTGGAATGGGCGGTGGAGATATTAAACTATTTGCAGTGATCGGTTTGGCGCTTGGGGT
AAAATTAACGGTTTTAGCATTCTTTTTATCGACGTTCGTTGGAACGATGTTTGGTCTGATTGGCATGGCAATAGGGCATG
TGAAGCGTGGCGAACCGATGCCGTTTGGACCAGCCATTGTCGTTGGTACACTTGTCGCTTATTTTTTTGGTGAAACGATC
ATCGATGCGTATGTTAAGGTTATGATGTAA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-87)

Type IV leader peptidase family (Peptidase_A24)

(103-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC Bacillus subtilis subsp. subtilis str. 168

49.388

98.394

0.486

Multiple sequence alignment