Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C6P70_RS18885 Genome accession   NZ_CP027388
Coordinates   3459165..3459797 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2011C-4251     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3454165..3464797
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6P70_RS18850 yheS 3454334..3456247 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  C6P70_RS18855 yheT 3456247..3457269 (+) 1023 WP_000057405.1 hydrolase -
  C6P70_RS18860 yheU 3457263..3457481 (+) 219 WP_000907085.1 YheU family protein -
  C6P70_RS18865 prkB 3457535..3458404 (+) 870 WP_001274680.1 phosphoribulokinase -
  C6P70_RS18870 yhfA 3458459..3458863 (-) 405 WP_001148904.1 OsmC family protein -
  C6P70_RS18885 crp 3459165..3459797 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C6P70_RS18890 yhfK 3459848..3461938 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  C6P70_RS18895 argD 3462005..3463225 (-) 1221 WP_000963797.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C6P70_RS18900 pabA 3463311..3463874 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  C6P70_RS18905 fic 3463906..3464508 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  C6P70_RS18910 yhfG 3464498..3464665 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=233416 C6P70_RS18885 WP_000242755.1 3459165..3459797(+) (crp) [Escherichia coli strain 2011C-4251]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=233416 C6P70_RS18885 WP_000242755.1 3459165..3459797(+) (crp) [Escherichia coli strain 2011C-4251]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467