Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C6P73_RS12940 Genome accession   NZ_CP027387
Coordinates   2461107..2461739 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2014C-3057     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2456107..2466739
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6P73_RS12915 yhfG 2456239..2456406 (+) 168 WP_000736860.1 YhfG family protein -
  C6P73_RS12920 fic 2456396..2456998 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  C6P73_RS12925 pabA 2457030..2457593 (+) 564 WP_000601850.1 aminodeoxychorismate synthase component 2 -
  C6P73_RS12930 argD 2457679..2458899 (+) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C6P73_RS12935 yhfK 2458966..2461056 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  C6P73_RS12940 crp 2461107..2461739 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C6P73_RS12950 yhfA 2462041..2462445 (+) 405 WP_001148908.1 OsmC family protein -
  C6P73_RS12955 prkB 2462500..2463369 (-) 870 WP_001274680.1 phosphoribulokinase -
  C6P73_RS12960 yheU 2463423..2463641 (-) 219 WP_000907085.1 YheU family protein -
  C6P73_RS12965 yheT 2463635..2464657 (-) 1023 WP_000057356.1 hydrolase -
  C6P73_RS12970 yheS 2464657..2466570 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=233340 C6P73_RS12940 WP_000242755.1 2461107..2461739(-) (crp) [Escherichia coli strain 2014C-3057]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=233340 C6P73_RS12940 WP_000242755.1 2461107..2461739(-) (crp) [Escherichia coli strain 2014C-3057]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment