Detailed information NTG0233246

Bioinformatically predicted

Overview

• Name: uvrC
• Type: Machinery gene
• Locus tag: AYN27_RS10500
• Genome accession: NZ_CP027380
• Coordinates: 1906442..1908274 (+)
• Length: 610 a.a.
• NCBI ID: WP_001283425.1
• Uniprot ID: -
• Organism: Escherichia coli strain 2013C-3250
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1901442..1913274

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AYN27_RS10470	dcyD	1901669..1902655 (+)	987	WP_001128215.1	D-cysteine desulfhydrase	-
AYN27_RS10475	tcyL	1902670..1903338 (+)	669	WP_001158220.1	cystine ABC transporter permease	-
AYN27_RS10480	tcyN	1903335..1904087 (+)	753	WP_001272994.1	L-cystine ABC transporter ATP-binding protein TcyN	-
AYN27_RS10485	sdiA	1904317..1905039 (+)	723	WP_001154271.1	transcriptional regulator SdiA	-
AYN27_RS10490	yecF	1905106..1905330 (-)	225	WP_000106474.1	DUF2594 family protein YecF	-
AYN27_RS30940	yecU	1905317..1905493 (-)	177	WP_000590347.1	protein YecU	-
AYN27_RS32245	-	1905576..1905647 (-)	72	Protein_1962	transcriptional regulator	-
AYN27_RS10495	letA	1905789..1906445 (+)	657	WP_000611339.1	UvrY/SirA/GacA family response regulator transcription factor	Regulator
AYN27_RS10500	uvrC	1906442..1908274 (+)	1833	WP_001283425.1	excinuclease ABC subunit UvrC	Machinery gene
AYN27_RS10505	pgsA	1908331..1908879 (+)	549	WP_001160187.1	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	-
AYN27_RS10525	yecA	1909529..1910194 (+)	666	WP_000847902.1	UPF0149 family protein YecA	-
AYN27_RS10530	tyrP	1910256..1911467 (-)	1212	WP_000797571.1	tyrosine transporter TyrP	-
AYN27_RS10535	yecH	1911658..1911897 (+)	240	WP_000377224.1	YecH family metal-binding protein	-
AYN27_RS10540	ftnA	1911935..1912432 (-)	498	WP_000917208.1	non-heme ferritin	-
AYN27_RS10545	yecR	1912603..1912926 (-)	324	WP_001237869.1	YecR-like lipofamily protein	-

Sequence

Protein

• Length: 610 a.a.
• Molecular weight: 68244.14 Da
• Isoelectric Point: 9.3685

>NTDB_id=233246 AYN27_RS10500 WP_001283425.1 1906442..1908274(+) (uvrC) [Escherichia coli strain 2013C-3250]
MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLL
EHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETASQNLEFEEAARIRDQIQAVRRVT
EKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLD
FNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEVKRMECFDI
SHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDDSKIPDVILIDGGKGQLAQAKNVFA
ELDVSWDKNHPLLLGVAKGVDRKVGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLET
IEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH

Nucleotide

• Length: 1833 bp

>NTDB_id=233246 AYN27_RS10500 WP_001283425.1 1906442..1908274(+) (uvrC) [Escherichia coli strain 2013C-3250]
GTGAGTGATCAGTTTGACGCAAAAGCGTTTTTAAAAACCGTAACCAGCCAGCCAGGCGTTTATCGCATGTACGATGCTGG
TGGTACGGTTATCTATGTCGGCAAAGCGAAAGACCTGAAAAAACGGCTTTCCAGCTATTTCCGTAGCAACCTCGCTTCGC
GCAAAACCGAAGCGCTGGTCGCCCAGATCCAGCAAATTGATGTAACGGTTACTCACACAGAAACCGAAGCGCTGTTGCTG
GAACACAACTACATCAAACTCTATCAGCCGCGTTACAACGTTTTGCTACGCGATGATAAATCATATCCTTTTATCTTCCT
GAGTGGTGATACCCACCCGCGTCTGGCGATGCATCGTGGTGCGAAGCATGCCAAAGGTGAATATTTCGGCCCGTTCCCGA
ATGGCTATGCCGTACGTGAAACACTGGCGCTACTGCAAAAGATTTTCCCCATTCGCCAGTGCGAAAATAGTGTTTATCGC
AATCGCTCGCGTCCGTGTCTGCAATACCAGATAGGGCGCTGTCTGGGACCGTGCGTTGAAGGACTGGTGAGTGAAGAAGA
ATACGCTCAGCAGGTCGAGTATGTGCGCCTGTTTTTGTCTGGCAAAGATGATCAGGTGCTTACGCAACTCATTAGTCGTA
TGGAAACTGCCAGCCAGAATCTGGAGTTTGAAGAAGCTGCACGTATTCGCGACCAAATTCAGGCGGTGCGACGCGTCACC
GAAAAACAATTCGTTTCCAATACCGGCGACGACCTCGACGTTATTGGTGTGGCGTTCGATGCGGGCATGGCTTGTGTCCA
CGTATTGTTCATTCGTCAGGGCAAAGTGCTCGGCAGCCGCAGCTATTTCCCGAAAGTGCCTGGCGGTACGGAACTGAGCG
AGGTGGTAGAAACCTTCGTAGGCCAGTTCTATTTACAAGGCAGCCAGATGCGCACCTTACCGGGTGAGATCCTGCTCGAT
TTTAATCTTAGCGATAAAACGCTGCTCGCCGATTCCCTTTCAGAACTGGCGGGACGCAAGATTAATGTTCAAACCAAACC
TCGCGGCGATAGGGCGCGTTATCTGAAACTCGCGCGCACCAATGCGGCGACGGCCTTAACCAGCAAACTTTCGCAGCAAT
CTACCGTTCACCAGCGACTGACCGCGCTTGCCAGCGTGTTGAAATTGCCGGAAGTGAAGCGGATGGAGTGCTTTGACATC
AGCCATACCATGGGCGAACAAACCGTCGCTTCCTGTGTGGTGTTTGATGCTAACGGCCCGCTGCGTGCGGAGTATCGGCG
CTATAACATTACAGGCATCACGCCGGGCGATGATTATGCGGCGATGAATCAGGTGCTGCGTCGGCGTTATGGTAAAGCCA
TTGACGACAGTAAGATCCCGGATGTGATCCTTATCGACGGCGGCAAAGGCCAGCTTGCGCAGGCGAAAAATGTCTTCGCC
GAACTGGATGTCTCATGGGATAAAAATCATCCACTGCTACTTGGCGTTGCCAAAGGAGTAGATCGTAAGGTTGGGCTGGA
AACACTGTTCTTTGAGCCGGAAGGTGAGGGATTCAGTTTGCCGCCAGATTCTCCCGCGCTGCATGTTATCCAGCATATTC
GCGATGAATCACACGATCACGCGATTGGCGGGCACCGTAAAAAACGGGCGAAGGTCAAAAATACCAGCTCCCTGGAAACC
ATTGAAGGCGTCGGGCCAAAACGTCGGCAAATGTTGTTGAAATATATGGGCGGTTTGCAAGGTTTACGTAACGCCAGCGT
CGAGGAAATTGCAAAAGTGCCGGGTATTTCGCAAGGTCTGGCAGAAAAGATCTTCTGGTCGTTGAAACATTGA

Domains

Predicted by InterProScan.

• UvrB/uvrC motif (UVR) (205-237)

• GIY-YIG catalytic domain (GIY-YIG) (18-93)

• UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom) (385-542)

• Helix-hairpin-helix domain (HHH_5) (558-609)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrC	Streptococcus pneumoniae TIGR4	37.891	99.508	0.377
uvrC	Streptococcus pneumoniae R6	37.562	99.508	0.374
uvrC	Streptococcus pneumoniae D39	37.562	99.508	0.374