Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   AYN27_RS00510 Genome accession   NZ_CP027380
Coordinates   108867..109499 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2013C-3250     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 103867..114499
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AYN27_RS00485 yhfG 103999..104166 (+) 168 WP_000736860.1 YhfG family protein -
  AYN27_RS00490 fic 104156..104758 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  AYN27_RS00495 pabA 104790..105353 (+) 564 WP_000601850.1 aminodeoxychorismate synthase component 2 -
  AYN27_RS00500 argD 105439..106659 (+) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  AYN27_RS00505 yhfK 106726..108816 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  AYN27_RS00510 crp 108867..109499 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  AYN27_RS00520 yhfA 109801..110205 (+) 405 WP_001148909.1 OsmC family protein -
  AYN27_RS00525 prkB 110260..111129 (-) 870 WP_001274680.1 phosphoribulokinase -
  AYN27_RS00530 yheU 111183..111400 (-) 218 Protein_99 YheU family protein -
  AYN27_RS00535 yheT 111394..112416 (-) 1023 WP_000057362.1 hydrolase -
  AYN27_RS00540 yheS 112416..114329 (-) 1914 WP_097601829.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=233217 AYN27_RS00510 WP_000242755.1 108867..109499(-) (crp) [Escherichia coli strain 2013C-3250]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=233217 AYN27_RS00510 WP_000242755.1 108867..109499(-) (crp) [Escherichia coli strain 2013C-3250]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment