Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C6P71_RS20865 Genome accession   NZ_CP027368
Coordinates   4025564..4026196 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2014C-3307     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4020564..4031196
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6P71_RS20840 yhfG 4020696..4020863 (+) 168 WP_000736860.1 YhfG family protein -
  C6P71_RS20845 fic 4020853..4021455 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  C6P71_RS20850 pabA 4021487..4022050 (+) 564 WP_000601844.1 aminodeoxychorismate synthase component 2 -
  C6P71_RS20855 argD 4022136..4023356 (+) 1221 WP_000963785.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C6P71_RS20860 yhfK 4023423..4025513 (-) 2091 WP_001345983.1 YccS/YhfK family putative transporter -
  C6P71_RS20865 crp 4025564..4026196 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C6P71_RS20875 yhfA 4026498..4026902 (+) 405 WP_001148908.1 OsmC family protein -
  C6P71_RS20880 prkB 4026957..4027826 (-) 870 WP_001274680.1 phosphoribulokinase -
  C6P71_RS20885 yheU 4027880..4028098 (-) 219 WP_000907085.1 YheU family protein -
  C6P71_RS20890 yheT 4028092..4029114 (-) 1023 WP_000057405.1 hydrolase -
  C6P71_RS20895 yheS 4029114..4031027 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=233039 C6P71_RS20865 WP_000242755.1 4025564..4026196(-) (crp) [Escherichia coli strain 2014C-3307]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=233039 C6P71_RS20865 WP_000242755.1 4025564..4026196(-) (crp) [Escherichia coli strain 2014C-3307]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467