Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C6P65_RS20195 Genome accession   NZ_CP027366
Coordinates   3856903..3857535 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 89-3156     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3851903..3862535
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6P65_RS20165 yheS 3852072..3853985 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  C6P65_RS20170 yheT 3853985..3855007 (+) 1023 WP_000057405.1 hydrolase -
  C6P65_RS20175 yheU 3855001..3855219 (+) 219 WP_000907085.1 YheU family protein -
  C6P65_RS20180 prkB 3855273..3856142 (+) 870 WP_001274680.1 phosphoribulokinase -
  C6P65_RS20185 yhfA 3856197..3856601 (-) 405 WP_001148908.1 OsmC family protein -
  C6P65_RS20195 crp 3856903..3857535 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C6P65_RS20200 yhfK 3857586..3859676 (+) 2091 WP_001345983.1 YccS/YhfK family putative transporter -
  C6P65_RS20205 argD 3859743..3860963 (-) 1221 WP_000963785.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C6P65_RS20210 pabA 3861049..3861612 (-) 564 WP_000601844.1 aminodeoxychorismate synthase component 2 -
  C6P65_RS20215 fic 3861644..3862246 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  C6P65_RS20220 yhfG 3862236..3862403 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=232955 C6P65_RS20195 WP_000242755.1 3856903..3857535(+) (crp) [Escherichia coli strain 89-3156]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=232955 C6P65_RS20195 WP_000242755.1 3856903..3857535(+) (crp) [Escherichia coli strain 89-3156]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467