Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C6P51_RS13700 Genome accession   NZ_CP027362
Coordinates   2520709..2521341 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 95-3192     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2515709..2526341
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6P51_RS13670 yheS 2515878..2517791 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  C6P51_RS13675 yheT 2517791..2518813 (+) 1023 WP_000057365.1 hydrolase -
  C6P51_RS13680 yheU 2518807..2519025 (+) 219 WP_000907085.1 YheU family protein -
  C6P51_RS13685 prkB 2519079..2519948 (+) 870 WP_001274680.1 phosphoribulokinase -
  C6P51_RS13690 yhfA 2520003..2520407 (-) 405 WP_001148912.1 OsmC family protein -
  C6P51_RS13700 crp 2520709..2521341 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C6P51_RS13705 yhfK 2521392..2523482 (+) 2091 WP_001400404.1 YccS/YhfK family putative transporter -
  C6P51_RS13710 argD 2523549..2524769 (-) 1221 WP_000963777.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C6P51_RS13715 pabA 2524855..2525418 (-) 564 WP_000601869.1 aminodeoxychorismate synthase component 2 -
  C6P51_RS13720 fic 2525450..2526052 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  C6P51_RS13725 yhfG 2526042..2526209 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=232855 C6P51_RS13700 WP_000242755.1 2520709..2521341(+) (crp) [Escherichia coli strain 95-3192]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=232855 C6P51_RS13700 WP_000242755.1 2520709..2521341(+) (crp) [Escherichia coli strain 95-3192]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTCAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment