Detailed information NTG0232839

Bioinformatically predicted

Overview

• Name: comP
• Type: Machinery gene
• Locus tag: CCD88_RS11540
• Genome accession: NZ_CP021724
• Coordinates: 2031869..2032318 (+)
• Length: 149 a.a.
• NCBI ID: WP_002214937.1
• Uniprot ID: A0AA44U8B7
• Organism: Neisseria meningitidis strain 12-330
• Function: DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	2033304..2033783	2031869..2032318	flank	986

Gene organization within MGE regions

Location: 2031869..2033783

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CCD88_RS11540 (CCD88_11735)	comP	2031869..2032318 (+)	450	WP_002214937.1	type IV pilin protein	Machinery gene
CCD88_RS13270 (CCD88_11740)	-	2032408..2032748 (-)	341	Protein_1969	5'-nucleotidase	-
CCD88_RS11550 (CCD88_11745)	-	2032860..2033072 (-)	213	WP_002224145.1	SWIM zinc finger domain-containing protein	-
CCD88_RS11555 (CCD88_11755)	-	2033304..2033777 (+)	474	Protein_1971	IS5/IS1182 family transposase	-

Sequence

Protein

• Length: 149 a.a.
• Molecular weight: 16834.81 Da
• Isoelectric Point: 9.7951

>NTDB_id=232839 CCD88_RS11540 WP_002214937.1 2031869..2032318(+) (comP) [Neisseria meningitidis strain 12-330]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK

Nucleotide

• Length: 450 bp

>NTDB_id=232839 CCD88_RS11540 WP_002214937.1 2031869..2032318(+) (comP) [Neisseria meningitidis strain 12-330]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCCTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG

Domains

Predicted by InterproScan.

• Type IV minor pilin ComP, DNA uptake sequence receptor (ComP_DUS) (28-107)

• Prokaryotic N-terminal methylation motif (N_methyl) (1-27)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comP	Neisseria gonorrhoeae MS11	100	100	1
comP	Neisseria meningitidis 8013	99.329	100	0.993
comP	Neisseria subflava NJ9703	49.66	98.658	0.49