Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C6P55_RS22245 Genome accession   NZ_CP027355
Coordinates   4179005..4179637 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2013C-4991     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4174005..4184637
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6P55_RS22220 yhfG 4174137..4174304 (+) 168 WP_000736862.1 YhfG family protein -
  C6P55_RS22225 fic 4174294..4174896 (+) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  C6P55_RS22230 pabA 4174928..4175491 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  C6P55_RS22235 argD 4175577..4176797 (+) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C6P55_RS22240 yhfK 4176864..4178954 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  C6P55_RS22245 crp 4179005..4179637 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C6P55_RS22255 yhfA 4179939..4180343 (+) 405 WP_001148908.1 OsmC family protein -
  C6P55_RS22260 prkB 4180398..4181267 (-) 870 WP_001274680.1 phosphoribulokinase -
  C6P55_RS22265 yheU 4181321..4181539 (-) 219 WP_000907085.1 YheU family protein -
  C6P55_RS22270 yheT 4181533..4182555 (-) 1023 WP_000057356.1 hydrolase -
  C6P55_RS22275 yheS 4182555..4184468 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=232801 C6P55_RS22245 WP_000242755.1 4179005..4179637(-) (crp) [Escherichia coli strain 2013C-4991]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=232801 C6P55_RS22245 WP_000242755.1 4179005..4179637(-) (crp) [Escherichia coli strain 2013C-4991]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment